Structure of PDB 3zkf Chain I Binding Site BS01
Receptor Information
>3zkf Chain I (length=85) Species:
9606
(Homo sapiens) [
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KAVIKNADMSEEMQQDSVECATQALEKYNIEKDIAAHIKKEFDKKYNPTW
HCIVGRNFGSYVTHETKHFIYFYLGQVAILLFKSG
Ligand information
>3zkf Chain H (length=10) Species:
9606
(Homo sapiens) [
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VGMHSKGTQT
Receptor-Ligand Complex Structure
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PDB
3zkf
Structural Analysis of the Regulation of the Dynll/Lc8 Binding to Nek9 by Phosphorylation
Resolution
2.6 Å
Binding residue
(original residue number in PDB)
I34 E35 K36
Binding residue
(residue number reindexed from 1)
I30 E31 K32
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Molecular Function
GO:0004857
enzyme inhibitor activity
GO:0005515
protein binding
GO:0019899
enzyme binding
GO:0030235
nitric-oxide synthase regulator activity
GO:0036487
nitric-oxide synthase inhibitor activity
GO:0042802
identical protein binding
GO:0044877
protein-containing complex binding
GO:0045505
dynein intermediate chain binding
GO:0060703
deoxyribonuclease inhibitor activity
GO:0097110
scaffold protein binding
Biological Process
GO:0006915
apoptotic process
GO:0006974
DNA damage response
GO:0007017
microtubule-based process
GO:0007286
spermatid development
GO:0021762
substantia nigra development
GO:0035721
intraciliary retrograde transport
GO:0035774
positive regulation of insulin secretion involved in cellular response to glucose stimulus
GO:0042326
negative regulation of phosphorylation
GO:0044458
motile cilium assembly
GO:0045019
negative regulation of nitric oxide biosynthetic process
GO:0110027
negative regulation of DNA strand resection involved in replication fork processing
Cellular Component
GO:0000776
kinetochore
GO:0005634
nucleus
GO:0005694
chromosome
GO:0005737
cytoplasm
GO:0005739
mitochondrion
GO:0005813
centrosome
GO:0005829
cytosol
GO:0005856
cytoskeleton
GO:0005868
cytoplasmic dynein complex
GO:0005874
microtubule
GO:0005875
microtubule associated complex
GO:0005886
plasma membrane
GO:0005929
cilium
GO:0008180
COP9 signalosome
GO:0015630
microtubule cytoskeleton
GO:0016020
membrane
GO:0030141
secretory granule
GO:0030286
dynein complex
GO:0035861
site of double-strand break
GO:0070821
tertiary granule membrane
GO:0072686
mitotic spindle
GO:0097542
ciliary tip
GO:0101003
ficolin-1-rich granule membrane
GO:1904115
axon cytoplasm
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Molecular Function
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Biological Process
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Cellular Component
External links
PDB
RCSB:3zkf
,
PDBe:3zkf
,
PDBj:3zkf
PDBsum
3zkf
PubMed
23482567
UniProt
P63167
|DYL1_HUMAN Dynein light chain 1, cytoplasmic (Gene Name=DYNLL1)
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