Structure of PDB 3rj1 Chain I Binding Site BS01

Receptor Information
>3rj1 Chain I (length=318) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QEQFVKRRRDMLEHINLAMNESSLALEFVSLLLSSVKESTGMSSMSPFLT
KKEYIELDILNKGWKLQSLNESKDLLRASFNKLSSILQNEHDYWNKIMQS
KDIRKQIQLLKKIIFEKELMYQIKKECALLISYGVSIENENKVIIELPNE
KFEIELLSLDDDSIVNHEQDLPKINDKRANLMLVMLRLLLVVIFKKTLRS
RISSPHPILGKVRFANYKLLLKKIIKDYVLDIVPGSSINKEIRAFDKLLN
IPRREAGAAAAAAAAAAAAAAAAAAAAAAAAAAGAAAAAAAAAAAAAAAA
EVEDFLHFIVAEYIQQKK
Ligand information
Ligand IDSE
InChIInChI=1S/H2Se/h1H2
InChIKeySPVXKVOXSXTJOY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0[SeH2]
CACTVS 3.341[Se]
FormulaSe
NameSELENIUM ATOM
ChEMBLCHEMBL1235891
DrugBank
ZINC
PDB chain3rj1 Chain I Residue 906 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB3rj1 Architecture of the Mediator head module.
Resolution4.3 Å
Binding residue
(original residue number in PDB)		L479 S480
Binding residue
(residue number reindexed from 1)		L157 S158
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003712 transcription coregulator activity
Biological Process
GO:0006357 regulation of transcription by RNA polymerase II
Cellular Component
GO:0016592 mediator complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3rj1, PDBe:3rj1, PDBj:3rj1
PDBsum3rj1
PubMed21725323
UniProtP32569|MED17_YEAST Mediator of RNA polymerase II transcription subunit 17 (Gene Name=SRB4)

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