Structure of PDB 3kxf Chain I Binding Site BS01

Receptor Information
>3kxf Chain I (length=276) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GSHSMRYFYTAMSRPGRGEPRFIAVGYVDDTQFVRFDSDAASPRTEPRAP
WIEQEGPEYWDRNTAIFKANTQTYRESLRNLRGYYNQSEAGSHIIQRMYG
CDLGPDGRLLRGHDQSAYDGKDYIALNEDLSSWTAADTAAQITQRKWEAA
RVAEARRAYLEGLCVEWLRRYLENGKETLQRADPPKTHVTHHPVSDHEAT
LRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVP
SGEEQRYTCHVQHEGLPKPLTLRWEP
Ligand information
>3kxf Chain S (length=13) Species: 10377 (Human herpesvirus 4 strain B95-8) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
LPEPLPQGQLTAY
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3kxf Hard wiring of T cell receptor specificity for the major histocompatibility complex is underpinned by TCR adaptability
Resolution3.1 Å
Binding residue
(original residue number in PDB)
Y7 N63 I66 F67 A69 T73 Y74 E76 S77 Y84 R97 Y99 S116 K146 W147 V152 A155 R156 Y159 W167 Y171
Binding residue
(residue number reindexed from 1)
Y7 N63 I66 F67 A69 T73 Y74 E76 S77 Y84 R97 Y99 S116 K146 W147 V152 A155 R156 Y159 W167 Y171
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:3kxf, PDBe:3kxf, PDBj:3kxf
PDBsum3kxf
PubMed20483993
UniProtP01889|HLAB_HUMAN HLA class I histocompatibility antigen, B alpha chain (Gene Name=HLA-B)

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