Structure of PDB 3jbp Chain I Binding Site BS01

Receptor Information
>3jbp Chain I (length=180) Species: 36329 (Plasmodium falciparum 3D7) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DIKLFKKWSYEEINIADLSLVDCIAVSQKACVYTPHTAGRYQKKRFRKAL
CPIVERLVNSMMMHGRNNGKKLKAIRIVAYAFEIIHLMTGENPLQVFVNA
VQKGGPREDSTRQAVDVSPLRRVNQAIYLICTGARNAAFRNIKSISECLA
EEIINCANESSSSYAIKKKDEIERVAKANR
Ligand information
>3jbp Chain A (length=1608) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
aaccugguugaucuugccaguagucauaugcuugucucaaagauuaagcc
augcaagugaaaguauauauauauauauguagaaacugcgaacggcucau
uaaaacaguuauagucuacuugacauuuauaaggauaacuacggaaaagc
uguagcuaauacuugcauuauccuuuuggauaaguauuuguuagaaggaa
uuauaacaaagaaguaacacguaaaguguguaucaaucgaguuucugacc
uaucagcuuuugauguuaggguauuggccuaacauggcuaugacggguaa
cggggaauuagaguucgauuccggagagggagccugagaaauagcuacca
caucuaaggaaggcagcaggcgcguaaauuacccaauucuaaagaagaga
gguagugacaagaaauaacaaugcaagguuuguauuggaauggugggaau
uuaaaaccuucccagaguaacaauuggagggcaagucuggugccagcagc
cgcgguaauuccagcuccaauagcguauauuaaaauuguugcaguuaaaa
cgcucguaguugaauuucaaagaaucauucuuuuuaaaauccgauuuugu
uacuuugaguaaauuagaguguucaaagcaaacaguuaaagcauuguguu
ugaauacuauagcauggaauaacaaaauugaacaagcuaaaauuuuuugu
ucuuauuuuggcuuaguuacgauuaauaggaguagcuuggggacauucgu
auucagaugucagaggugaaauucuuagauuuucuggagacgaacaacug
cgaaagcauuugucuaaaauacuuccauuaaucaagaacgaaaguuaagg
gagugaagacgaucagauaccgucguaaucuuaaccauaaacuaugccga
cuagguguuggaugaagugcuuccuucaguaccuuaugagaaaucaaagu
cuuuggguucuggggcgaguauucgcgcaagcgagaaaguuaaaagaauu
gacggaagggcaccaccaggcguggagcuugcggcuuaauuugacucaac
acggggaaacucacuaguuuaagacauuggauggugaugcauggccguuu
uuaguucgugaaugauuugucugguuaauuccgauaacgaacgagaucuu
aaccugcuaauuagcggcgaguacacuguacuugcugcuucuuagaggaa
cauugugugucuaacacaaggaaguuuaaggcaacaacaggucugugaug
uccuuagaugaacuaggcugcacgcgugcuacacugauauauauaacgag
uaaaauaugcuugcauacuuuuccuccgccgaaaggcguagguaaucuuu
aucaauauauaucgugauggggauagauuauugcaauuauuaaucuugaa
cgaggaaugccuaguaagcaugauucaucagauugugcuaacuacguccc
ugcccuuuguacacaccgcccgucgcuccuaccgauugaaagauaugaug
aauuguuuggacaagaaaaauuuuuucuggaaaaaccguaaauccuaucu
uuuaaaggaaggagaagucguaacaagguuuccguaggugaaccugcgga
aggaucau
...<<<<<.[.((((>>>>><<<<.<<<<<<...<<<...<......<<<
.<<<..<<....<<...<<<<<<..>>>>>>...>>.>>......<<...
.....<<<..<<..<<...<<<<........<<.....<<<<<<.....>
>>>>>......>>....<<<<<<....>>>>>>...<<<<<<<.<.....
.>.>>>>>>>.......<<<.....>>>....>>>>..>>>>..>>>.<<
<....<<<....<<<<<<<<.......>>>>>>>>>>>......>>>...
<<<<<<<<....>>>>...>>>>.>>.<<.<<<..........>>>.>>.
<.<<....>>.>...>>>>>>.........<<<....<<<.....>>>..
>>>..>....>>>.....<<<<<<<<<.>>>>>>>>>......<<<<<<.
........>>>>>>.........<<<<<((......<<<<.....<<..)
)>>.......>>>>.>>>>>..>>>>>>>>>>.........<<<((....
.<.<<...<<<.<<....<<<<.<....>.>>>>..<<<......>>><<
<<<<.<<.......<<...<.......>.<<<<.......<<<.>>>>>>
>...>>......>>.>>..>>>>.....<<<<<.<<.<.<<<.<......
....>.>>>.>.>>.>>>.>>.>>....<<<<<<..<<..<<<<<..<<<
.<<<<<<.<...<<<......>>>......>.>>>>>>.>>>.......<
<....>>...>>>>>.>>.>>>.>>>...>>>...>>.>....<<<<<<.
..<<...<<<<.<.....>.>>>>...>>>>>>>>..........<<<.<
<.<<<<<<<<<<.<<<<..>>>>.>>>>>>>>>>...<<..))>>...>>
.....>>>.>>>.<<<.....<<<<<....>>>>>...>>>..)))).]<
<<<<.<<<<<<<..<<.<<<<<<..<<<.<<<<<<......<<.......
.>>..........<<<<<<<....<<.>>...<<.<<<..<<<<<<<<<.
...<<<<<<<<<...>>>...<<<......>>>...>>>>>>....<<<<
<.<<<..<<...<<<<<<<<<<<<...>>>>>>>>>>>>...>>.>>>..
..<<<<<<.....>>>>>>.......>>>>>....>>>.>>>...>.>>>
>>>>.....>>>>>>>...>>.>>>>.>>>.....<<<<<<<<.....<<
...<.<<<<<..>>>>>.>...<<<.<<<<....>>>>.>>>....>>..
.....>>>>>>>>......<....<<<<<<..........>>>>>>....
>.....>>>>>>....<<<<<<<<.......>>>>>>>>......>>...
>>>>>>>>>>.>>....<..<<.<.<<<<<.<<....<<.<<<<<.<<<.
.<<.<<<<...<<.<<<<<.>>>.>>.>>...>>>>.>>..>>>.>>>>>
>.>...>>.>>>>>..>.>>...>.....<<<<<<<<<....>>>>>>>>
>.......
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3jbp Dynamical features of the Plasmodium falciparum ribosome during translation.
Resolution6.7 Å
Binding residue
(original residue number in PDB)		R46 Q48 K49 K50 R51 K54 R62 N65 M69 H70 R72 N73 G75 K76 K77 L78 K79 R82 R136 N139 Y143 R150 F154 R155 I157 S159 I160
Binding residue
(residue number reindexed from 1)		R40 Q42 K43 K44 R45 K48 R56 N59 M63 H64 R66 N67 G69 K70 K71 L72 K73 R76 R121 N124 Y128 R135 F139 R140 I142 S144 I145
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003729 mRNA binding
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0000028 ribosomal small subunit assembly
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0015935 small ribosomal subunit
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:3jbp, PDBe:3jbp, PDBj:3jbp
PDBsum3jbp
PubMed26432834
UniProtQ8IBN5

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