Structure of PDB 3j1o Chain I Binding Site BS01

Receptor Information
>3j1o Chain I (length=318) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QEQFVKRRRDMLEHINLAMNESSLALEFVSLLLSSVKESTGMSSMSPFLT
KKEYIELDILNKGWKLQSLNESKDLLRASFNKLSSILQNEHDYWNKIMQS
KDIRKQIQLLKKIIFEKELMYQIKKECALLISYGVSIENENKVIIELPNE
KFEIELLSLDDDSIVNHEQDLPKINDKRANLMLVMLRLLLVVIFKKTLRS
RISSPHPILGKVRFANYKLLLKKIIKDYVLDIVPGSSINKEIRAFDKLLN
IPRREAGAAAAAAAAAAAAAAAAAAAAAAAAAAGAAAAAAAAAAAAAAAA
EVEDFLHFIVAEYIQQKK
Ligand information
>3j1o Chain N (length=25) Species: 4932 (Saccharomyces cerevisiae) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
IFKIVQSRLMSTSYHLNSTLESLYD
Receptor-Ligand Complex Structure
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PDB3j1o Interaction of the mediator head module with RNA polymerase II.
Resolution16.0 Å
Binding residue
(original residue number in PDB)
H210 I211 A214 E217
Binding residue
(residue number reindexed from 1)
H14 I15 A18 E21
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003712 transcription coregulator activity
Biological Process
GO:0006357 regulation of transcription by RNA polymerase II
Cellular Component
GO:0016592 mediator complex

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:3j1o, PDBe:3j1o, PDBj:3j1o
PDBsum3j1o
PubMed22579255
UniProtP32569|MED17_YEAST Mediator of RNA polymerase II transcription subunit 17 (Gene Name=SRB4)

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