Structure of PDB 2i2r Chain I Binding Site BS01

Receptor Information
>2i2r Chain I (length=133) Species: 10116 (Rattus norvegicus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AGVAAWLPFARAAAIGWMPVANCPMPLNKRQDELIVLNVSGRRFQTWRTT
LERYPDTLLGSTEKEFFFNEDTKEYFFDRDPEVFRCVLNFYRTGKLHYPR
YECISAYDDELAFYGILPEIIGDCCYEEYKDRK
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain2i2r Chain I Residue 605 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB2i2r Three-dimensional structure of the KChIP1-Kv4.3 T1 complex reveals a cross-shaped octamer
Resolution3.35 Å
Binding residue
(original residue number in PDB)		H104 C131 C132
Binding residue
(residue number reindexed from 1)		H97 C124 C125
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005249 voltage-gated potassium channel activity
Biological Process
GO:0006813 potassium ion transport
GO:0051260 protein homooligomerization
Cellular Component
GO:0008076 voltage-gated potassium channel complex

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Molecular Function
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Cellular Component
External links
PDB RCSB:2i2r, PDBe:2i2r, PDBj:2i2r
PDBsum2i2r
PubMed17057713
UniProtQ62897|KCND3_RAT A-type voltage-gated potassium channel KCND3 (Gene Name=Kcnd3)

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