Structure of PDB 1fnt Chain I Binding Site BS01
Receptor Information
>1fnt Chain I (length=222) Species:
4932
(Saccharomyces cerevisiae) [
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TTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAA
DTEAVTQLIGSNIELHSLYTSREPRVVSALQMLKQHLFKYQGHIGAYLIV
AGVDPTGSHLFSIHAHGSTDVGYYLSLGSGSLAAMAVLESHWKQDLTKEE
AIKLASDAIQAGIWNDLGSGSNVDVCVMEIGKDAEYLRNYLTPNVREEKQ
KSYKFPRGTTAVLKESIVNICD
Ligand information
Ligand ID
MG
InChI
InChI=1S/Mg/q+2
InChIKey
JLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
Software
SMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0
[Mg+2]
CACTVS 3.341
[Mg++]
Formula
Mg
Name
MAGNESIUM ION
ChEMBL
DrugBank
DB01378
ZINC
PDB chain
1fnt Chain I Residue 1001 [
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Receptor-Ligand Complex Structure
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PDB
1fnt
Structural basis for the activation of 20S proteasomes by 11S regulators.
Resolution
3.2 Å
Binding residue
(original residue number in PDB)
I163 D166 L167
Binding residue
(residue number reindexed from 1)
I163 D166 L167
Annotation score
4
Enzymatic activity
Catalytic site (original residue number in PDB)
T1 D17 R19 K33 G47 S129 D166 S169
Catalytic site (residue number reindexed from 1)
T1 D17 R19 K33 G47 S129 D166 S169
Enzyme Commision number
3.4.25.1
: proteasome endopeptidase complex.
Gene Ontology
Molecular Function
GO:0004298
threonine-type endopeptidase activity
Biological Process
GO:0051603
proteolysis involved in protein catabolic process
Cellular Component
GO:0005839
proteasome core complex
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Molecular Function
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Biological Process
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Cellular Component
External links
PDB
RCSB:1fnt
,
PDBe:1fnt
,
PDBj:1fnt
PDBsum
1fnt
PubMed
11081519
UniProt
P25043
|PSB2_YEAST Proteasome subunit beta type-2 (Gene Name=PUP1)
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