Structure of PDB 8z9r Chain H Binding Site BS01

Receptor Information
>8z9r Chain H (length=449) Species: 126796 (Thogoto virus (isolate SiAr 126)) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SVGTTFRTLLKRDTDWDVIPTPRVEPNVPRIEGRRWTQMKKLPLLKEKEG
PPSPWRALLLGADSEYIVCPPGTDQEAISWIHSQSEIECIRESKSTPASV
ITCLTSSLQSFAEGNPVRSRIHEDIIAFGINKKQEKKQSASSSASGEWKR
AEYQVEEMSLPPWVEEEMVLLRSDQEDNWIELEKNAIYTEVDGVAEGLVD
KYIEIVGRTKVASVIEKWQIAATRTFSQLHTDRSRITACPIITRDPSGNC
QFWGMVLLGPHHVKRDTDNAPLLIAEIMGEDTEEKYPKHSVFSLKVEEKQ
FLLSLKITSFSRNKLYTFSNIRRVLIQPASIYSQVVLSRAAENNSLNLEV
NPEIQLYLEGAQRGMTLYQWVRMILCLEFLMAIYNNPQMEGFLANMRRLH
MSRHAMMERRQVFLPFGSRPEDKVNECIINNPIVAYLAKGWNSMPNVYY
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8z9r Cryo-EM structures of Thogoto virus polymerase reveal unique RNA transcription and replication mechanisms among orthomyxoviruses
Resolution2.58 Å
Binding residue
(original residue number in PDB)		S268 G302 K305 K306 K309 Y326 D441 N442 K461 K479 I480 S482
Binding residue
(residue number reindexed from 1)		S95 G129 K132 K133 K136 Y153 D268 N269 K288 K306 I307 S309
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Cellular Component
GO:0042025 host cell nucleus
GO:0044423 virion component

View graph for
Cellular Component
External links
PDB RCSB:8z9r, PDBe:8z9r, PDBj:8z9r
PDBsum8z9r
PubMed38816392
UniProtP27194|PA_THOGV Polymerase acidic protein (Gene Name=Segment)

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