Structure of PDB 8z9h Chain H Binding Site BS01

Receptor Information
>8z9h Chain H (length=449) Species: 126796 (Thogoto virus (isolate SiAr 126)) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SVGTTFRTLLKRDTDWDVIPTPRVEPNVPRIEGRRWTQMKKLPLLKEKEG
PPSPWRALLLGADSEYIVCPPGTDQEAISWIHSQSEIECIRESKSTPASV
ITCLTSSLQSFAEGNPVRSRIHEDIIAFGINKKQEKKQSASSSASGEWKR
AEYQVEEMSLPPWVEEEMVLLRSDQEDNWIELEKNAIYTEVDGVAEGLVD
KYIEIVGRTKVASVIEKWQIAATRTFSQLHTDRSRITACPIITRDPSGNC
QFWGMVLLGPHHVKRDTDNAPLLIAEIMGEDTEEKYPKHSVFSLKVEEKQ
FLLSLKITSFSRNKLYTFSNIRRVLIQPASIYSQVVLSRAAENNSLNLEV
NPEIQLYLEGAQRGMTLYQWVRMILCLEFLMAIYNNPQMEGFLANMRRLH
MSRHAMMERRQVFLPFGSRPEDKVNECIINNPIVAYLAKGWNSMPNVYY
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8z9h Cryo-EM structures of Thogoto virus polymerase reveal unique RNA transcription and replication mechanisms among orthomyxoviruses
Resolution2.7 Å
Binding residue
(original residue number in PDB)		S268 G302 K306 K309 Y326 N442 K461 K479 I480 T481 S482 F483
Binding residue
(residue number reindexed from 1)		S95 G129 K133 K136 Y153 N269 K288 K306 I307 T308 S309 F310
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Cellular Component
GO:0042025 host cell nucleus
GO:0044423 virion component

View graph for
Cellular Component
External links
PDB RCSB:8z9h, PDBe:8z9h, PDBj:8z9h
PDBsum8z9h
PubMed38816392
UniProtP27194|PA_THOGV Polymerase acidic protein (Gene Name=Segment)

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