Structure of PDB 8vev Chain H Binding Site BS01

Receptor Information
>8vev Chain H (length=214) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EVKLEESGGGLVQPGGSMKLSCVASGFSFTNYWMNWVRQSPEKGLEWVAE
ISLKSSNYVTYYAESVKGRFTISSDKSKRSVYLQMNNLRAEDTGIYFCSL
WQTWFAYWGQGTLVTVSSAKTTPPSVYPLAPGSTNSMVTLGCLVKGYFPE
PVTVTWNSGSLSSGVHTFPAVLQSDLYTLSSSVTVPSSTWPSETVTCNVA
HPASSTKVDKKIVP
Ligand information
Ligand ID6MD
InChIInChI=1S/C11H15N5O4/c1-12-9-6-10(14-3-13-9)16(4-15-6)11-8(19)7(18)5(2-17)20-11/h3-5,7-8,11,17-19H,2H2,1H3,(H,12,13,14)/t5-,7-,8-,11-/m1/s1
InChIKeyVQAYFKKCNSOZKM-IOSLPCCCSA-N
SMILES
SoftwareSMILES
ACDLabs 12.01n2c1c(ncnc1n(c2)C3OC(C(O)C3O)CO)NC
CACTVS 3.385CNc1ncnc2n(cnc12)[C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O
OpenEye OEToolkits 1.7.6CNc1c2c(ncn1)n(cn2)C3C(C(C(O3)CO)O)O
OpenEye OEToolkits 1.7.6CNc1c2c(ncn1)n(cn2)[C@H]3[C@@H]([C@@H]([C@H](O3)CO)O)O
CACTVS 3.385CNc1ncnc2n(cnc12)[CH]3O[CH](CO)[CH](O)[CH]3O
FormulaC11 H15 N5 O4
NameN-methyladenosine
ChEMBLCHEMBL383144
DrugBank
ZINCZINC000004245632
PDB chain8vev Chain H Residue 304 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB8vev Structure of a mouse IgG antibody antigen-binding fragment (Fab) targeting N6-methyladenosine (m6A), an RNA modification, m6A nucleoside ligand
Resolution3.06 Å
Binding residue
(original residue number in PDB)		W33 E50 W101
Binding residue
(residue number reindexed from 1)		W33 E50 W101
Annotation score1
External links