Structure of PDB 8t3w Chain H Binding Site BS01

Receptor Information
>8t3w Chain H (length=94) Species: 8355 (Xenopus laevis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TRKESYAIYVYKVLKQVHPDTGISSKAMSIMNSFVNDVFERIAGEASRLA
HYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSAK
Ligand information
>8t3w Chain I (length=146) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
tcgagaatcccggtgccgaggccgctcaattggtcgtagacagctctagc
accgcttaaacgcacgtacgcgctgtcccccgcgttttaaccgccaaggg
gattactccctagtctccaggcacgtgtcagatatatacatccgat
Receptor-Ligand Complex Structure
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PDB8t3w Cryo-EM structure of Bre1-nucleosome complex in state 2
Resolution3.25 Å
Binding residue
(original residue number in PDB)
S56 S87 T88
Binding residue
(residue number reindexed from 1)
S25 S56 T57
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Cellular Component
GO:0000786 nucleosome
GO:0005634 nucleus
GO:0005694 chromosome

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Molecular Function

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Cellular Component
External links
PDB RCSB:8t3w, PDBe:8t3w, PDBj:8t3w
PDBsum8t3w
PubMed37872231
UniProtP02281|H2B11_XENLA Histone H2B 1.1

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