Structure of PDB 8rcf Chain H Binding Site BS01

Receptor Information
>8rcf Chain H (length=311) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GPQPISRLEQCGINANDVKKLEEAGFHTVEAVAYAPKKELINIKGISEAK
ADKILAEAAKLVPMGFTTATEFHQRRSEIIQITTGSKELDKLLQGGIETG
SITEMFGEFRTGKTQICHTLAVTCQLPIDRGGGEGKAMYIDTEGTFRPER
LLAVAERYGLSGSDVLDNVAYARAFNTDHQTQLLYQASAMMVESRYALLI
VDSATALYRTDYSGRGELSARQMHLARFLRMLLRLADEFGVAVVITNQVV
AQVDPKKPIGGNIIAHASTTRLYLRKGRGETRICKIYDSPCLPEAEAMFA
INADGVGDAKD
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8rcf RAD51 protects abasic sites to prevent replication fork breakage.
Resolution3.4 Å
Binding residue
(original residue number in PDB)
R229 R241 Q242 V270 A271 V273 G289
Binding residue
(residue number reindexed from 1)
R209 R221 Q222 V250 A251 V253 G261
External links
PDB RCSB:8rcf, PDBe:8rcf, PDBj:8rcf
PDBsum8rcf
PubMed39178838
UniProtQ06609|RAD51_HUMAN DNA repair protein RAD51 homolog 1 (Gene Name=RAD51)

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