Structure of PDB 8qu1 Chain H Binding Site BS01

Receptor Information
>8qu1 Chain H (length=85) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TVIVERWWKVPLAGEGRKPRLHRRHRVYKLVEDTKHRPKENLELILTQLV
SVKKSLGRNRLLPQGLAVYASPENKKLFEEEKLLR
Ligand information
>8qu1 Chain A (length=938) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gcuaaaccuagccccaaacccacuccaccuuacuaccaauaaaguauagg
cgauagaaauugggcgcaauagauauaguaccgcaagggaaagaugaaaa
auaccaagcauaauauagcaaggacuaaccccuauaccuucugaugaauu
aacuagaaauaacuuugcaaggagagccaaagcuaagacccccgaaacca
gacgaagccuggugauagcugguuguccaagauagacaacuuuaaauuug
cccacagaaccaaauccccuuguaaauuuaacuguuaguccaaagaggaa
cagcucuuuggacacuaggaaaaaaccuuguagagagaguaaaaaauuua
acacccauaguaggccuaaaagcagccaccaauuaagaaagcguucaagc
ucaacacucccaaacauauaacugaacuccucacacccaauuggaccaau
cuaucacccuauagaagaacuaauguuaguauaaguaacaugaaaacauu
cuccuccgcauaagccugcgucagaucacugacaauuaacagcccaauau
cuacaaucaaccaacaagucauuauuacccucacugucaacccaaggcau
gcucauaaggaaagguuaaaaaaaguaaaaggaaacaucaccucuagcau
caccaguauuagaggccagcugucucuuacuuuuaaccagugaaauugac
cugcccgugaggcgggcauaacacagcaagacgagacccuauggagcuuu
aauuuauuaaugcaaacaccugcauuaaaaauacaugcuaagacuucacc
agucaaagcgaacaguuacccuaggguaucuacuuuauuccucccuguac
gaaaggacaagagaaauaaggccuacuucacaaagcgccuucuaaaugau
aucaucucaacuuaauacccacacccaagaacaggguu
<<<.......<<<<................................<<..
...>>.......>>.>>.............<<....>>............
......>>>...........<<<.......>>>...<.<....>.>.<<<
<<<.........<<<.<<..<<....>>...>>.>>>...<<.<..<<<<
<.<...>.>>>>...>..>.>>..<<<<<<....<.><<<.<<<<<<<<<
<.....<<......>>.....>>>>>>>>>>..>>>.<<<<<<<<<<...
...>>>>>>>>>>...<<<......>>>....<<<.<<<...<.......
.......<....<<<.........>>>....>.......<<<......>>
>.....................>...>>>>>>........>>>>>>...<
<<<<......>>>>>.........>>>>>><......<<..<<<....>>
><<<<..<<<<........<<<<<....>>>>>......<<<...<<<<.
......................>>>>.......>>>.....<<..>>.>>
>>.....>>>>..<<<<...<<<<<<<<.<<.........<<<<<<....
.........>>>>>>........>>.>>>>>>>>>>>>.>>.....>...
..<<<<<.....>>>>>.......<<..<<<.....<<<<<.<<<<<<..
..<<..<<<<<<<<......>>>>>>>.>>>.....<<<..<<<<.....
>>>>..>>>....>>>>..>>>>>>>..>>>.>>..<<<.<<<.......
..........>>>.>>><<<<<...<<<....>>>.>>>>>.<<<.<...
.........>.>>>........<<<<.......>>>>.
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB8qu1 GTPBP8 plays a role in mitoribosome formation in human mitochondria.
Resolution2.74 Å
Binding residue
(original residue number in PDB)		L64 A65 G66 E67 L82 D85 K87 K91 S117 N121
Binding residue
(residue number reindexed from 1)		L12 A13 G14 E15 L30 D33 K35 K39 S55 N59
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
Biological Process
GO:0006412 translation
GO:0032543 mitochondrial translation
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005761 mitochondrial ribosome
GO:0005762 mitochondrial large ribosomal subunit
GO:0005840 ribosome
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8qu1, PDBe:8qu1, PDBj:8qu1
PDBsum8qu1
PubMed38969660
UniProtQ9BYD2|RM09_HUMAN Large ribosomal subunit protein bL9m (Gene Name=MRPL9)

[Back to BioLiP]