Structure of PDB 8om2 Chain H Binding Site BS01

Receptor Information
>8om2 Chain H (length=154) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SLVKLANTCAHLQNCSKVRVALTSIPYTKLQLQFAYNLYQQGFLSSLQKG
STMGPDKDFVEVTPDNISTRRLWVGLKYRDNKPVLSSCKLISKPNSRIHL
PMEDMKKLCSGVTIRNIKPLQPGELILVRAHNNIMDINEAISKKLDGEVL
CRVK
Ligand information
>8om2 Chain r (length=1486) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
auaagaauaugauguugguucagauuaagcgcuaaauaaggacaugacac
augcgaaucauacguuuauuauugauaagauaauaaauaugugguguaaa
cgugaguaauuuuauuaggaauuaaugaacuauagaauaagcuaaauacu
uaauauauaaaaaggauauauaauauauuuaucuauagucaagccaauaa
ugguuuagguaguagguuuauuaagaguuaaaccuagccaacgauccaua
aucgauaaugaaaguuagaacgaucacguugacucugaaauauagucaau
aucuauaagauacagcagugaggaauauuggacaaugaucgaaagauuga
uccaguuacuuauuaggaugauauauaaauauauauauauaaauugauua
aaaauaaaauccauaaauaauuaaaauaaugauauuaauuaccauauauu
uuuauauggauauauuuuaauaguccugacuaauauuugugccagcaguc
gcgguaacacaaagagggcgagcguuaaucauaaugguuuaaaggauccg
uagaaugaauuauauauuauaauuuagaguuaauaaaauuaauuaaagaa
uuauaauaguaaagaugaaauaaauaauuauaagacuaauauaugugaaa
auauuaauuaaauauuaacugacauugagggauuaaaacuagaguagcga
aacggauucgauacccguguaguucuaguaguaaacuaugaauacaauua
uuuauauauauauauauaaauaauaaaugaaaaugaaaguauuccaccug
aagaguacguuagcaauaaugaaacucaaaacaauagacgguuacagacu
uaagcaguggagcauguuauuuaauucgauaauccacgacuaaccuuacc
auauuuugaauauuauaauaauuaaauuauuauauuacaggcguuacauu
guugucuuuaguucgugcugcaaaguuuuagauuaaguucauaaacgaac
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aauauaaagaaaggaauuaagacaaucauaaugauccuuauaauaugggu
aauagacgugcuauaauaaaaugauaauaaaauuauauaaaauauauuua
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aaauaauaugaauuaaugcgaaguugaaauacaguuaccguaggggaacc
ugcggugggcuuauaaauaucuuaaauauucuuaca
....<<<<..[.((((.>>>>.<<<<.<<<<<..<<<<<<<<.....<<<
.<<<..<<<..<<<<<<<<<<<<.....>>>>>>>>>>..>>>>>.....
<<<........<<<<<.<<.........<<<<<<<<.<<<<.......>>
>>...........<<<<<<<<.>>>>>>>>.>>>>>>>>....>>>>>>>
<<<....<<<..<<<<<<<<........>>>>>>>>>>>......>>>..
<<<<.<<<<....>>>>...>>>>.>>><<<<<<.........>>>>>><
<<<.....>>>>..>>>>>>.........<<<....<<<<....>>>>..
>>>..>>.>>>>>>.<<<<..<<<<<<........>>>>>>..<<.....
.>>.....>>>>..<<<<<<<<..............>>>>><<<<<<<..
..>>>>>>><<..>>>>>....<<<<<(((.....<<<<.....<<.)))
>>.......>>>>.>>>>>..>>>>>>>>>.....<<<((.....<<<<.
..<.<<.<<<<<<<...>>>>>>>...<<<<<<<<...<<<<<<<<<<..
<<<<<<<...................>>>>>>>..>>.......<<....
>>.>>>>>>>>.>>>>>>>>...>>>...>>>>....<<<<<<...<<..
.<<<<.........>>>>...>>>>>>>>..........<<<<<<.<<<<
<<<<<<<<<..>>>>>>>>>>>>>..<<..))>>....>>>>>>.>>>.<
<.......<<<<....>>>>.....>>..)))).]<<.<<...<<<<...
.<.<<<<<..<<<<<<<<<<............................<<
<<<<<.....<<.<<<<<<<<<<.>>>>>>>>>>.>>.<<<.<<..<<<<
<<<<<<<<..<<<<<<<<<....>>>....<<......>>....>>>>>>
.....<<<.<<<<<<<<........>>>>>>>>..<<<<<<<<<.....>
>>>>>>>>....>>>...>>>>>>>...>>>>>>>>>>...>>>>>>>..
.>>.>>>>>>>>.....<<<<<<........<<<..<<..<<<<<<....
..>>>>>>..>>....>>>......>>>>>>......<<<<<........
>>>>>..........<....<<<<<<<........>>>>>>>....>...
..>>>>>.....<<.<<<<<.........>>>>>>>.....>.....>>>
>..>>..>>....<.<<<.<.<<<<<<<<..<<<<<<<<<.<<<...<<<
..<<<.<<<<<...<<<<<<<..>>>>>>>...>>>>>>>>..>>>..>>
>>>>>>>>>>..>>>>>>>>..>.>>>..>.....<<<<<<<<<....>>
>>>>>>>.............................
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8om2 METTL17 is an Fe-S cluster checkpoint for mitochondrial translation.
Resolution2.57 Å
Binding residue
(original residue number in PDB)
S2 K5 A7 N8 A11 H12 Q14 N15 V19 T29 K30 P65 S69 K94 P95 N96 R98 H100 V113 K119 R130 A131 H132 N133 E149
Binding residue
(residue number reindexed from 1)
S1 K4 A6 N7 A10 H11 Q13 N14 V18 T28 K29 P64 S68 K93 P94 N95 R97 H99 V112 K118 R129 A130 H131 N132 E148
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
GO:0032543 mitochondrial translation
Cellular Component
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005763 mitochondrial small ribosomal subunit
GO:0005840 ribosome
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:8om2, PDBe:8om2, PDBj:8om2
PDBsum8om2
PubMed38199006
UniProtQ03799|RT08_YEAST Small ribosomal subunit protein uS8m (Gene Name=MRPS8)

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