Structure of PDB 8jkl Chain H Binding Site BS01

Receptor Information
>8jkl Chain H (length=108) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GKLRQWLIDQIDSGKYPGLVWENEEKSIFRIPWKHAGKQDYNREEDAALF
KAWALFKGKFREGIDKPDPPTWKTRLRCALNKSNDFEELVERSQLDISDP
YKVYRIVP
Ligand information
Receptor-Ligand Complex Structure
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PDB8jkl Molecular basis for the functional roles of the multimorphic T95R mutation of IRF4 causing human autosomal dominant combined immunodeficiency.
Resolution2.94 Å
Binding residue
(original residue number in PDB)		W54 H56 A57 K59 Q60 Y62 K94 R98 N102 K103
Binding residue
(residue number reindexed from 1)		W33 H35 A36 K38 Q39 Y41 K73 R77 N81 K82
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000976 transcription cis-regulatory region binding
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:8jkl, PDBe:8jkl, PDBj:8jkl
PDBsum8jkl
PubMed37683642
UniProtF2Z3D5

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