Structure of PDB 8evj Chain H Binding Site BS01

Receptor Information
>8evj Chain H (length=94) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RSRKESYSIYVYKVLKQVHPDTGISSKAMGIMNSFVNDIFERIAGEASRL
AHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSS
Ligand information
>8evj Chain I (length=138) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
tcttcagctggttgctgagagttgcagcattgctgagtcttagcaatgga
tacttcccgattcccctcacaaaaataggtcagtctgtctggctagttct
gtacttgcagacacagggcatgtggggttcctattttt
Receptor-Ligand Complex Structure
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PDB8evj Structural basis of cooperative targeting of the CX3CR1 nucleosome
Resolution4.1 Å
Binding residue
(original residue number in PDB)		R83 S84 T85
Binding residue
(residue number reindexed from 1)		R56 S57 T58
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Biological Process
GO:0002227 innate immune response in mucosa
GO:0006334 nucleosome assembly
GO:0019731 antibacterial humoral response
GO:0042742 defense response to bacterium
GO:0050830 defense response to Gram-positive bacterium
GO:0061844 antimicrobial humoral immune response mediated by antimicrobial peptide
Cellular Component
GO:0000786 nucleosome
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005694 chromosome
GO:0005829 cytosol
GO:0070062 extracellular exosome

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Cellular Component
External links
PDB RCSB:8evj, PDBe:8evj, PDBj:8evj
PDBsum8evj
PubMed38267599
UniProtQ16778|H2B2E_HUMAN Histone H2B type 2-E (Gene Name=H2BC21)

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