Structure of PDB 8ev3 Chain H Binding Site BS01

Receptor Information
>8ev3 Chain H (length=183) Species: 4896 (Schizosaccharomyces pombe) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DIYKDETLTIPKGVTVDIKARNVTVTGPRGTLKQNLRHVDIEMKKQGNTI
KFIVWHGSRKHNACIRSVYSIINNMIIGVTQGFRYKMRLVYAHFPININL
TENGTVVEIRNFLGERITRVIKCLPGVTVSISSAVKDEIILEGNSLENVS
QSAANIKQICNVRNKDIRKFLDGIYVSERGNIE
Ligand information
>8ev3 Chain 1 (length=1452) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uugaccucaaaucagguaggacuacgcgcugaacaauaagcgcaggaaaa
gaaaauaaccaugauucccucaguaacggugaagcgggaaaagcucaaau
uugaaaucuggcaacauuucuuuuguuguccgaguuguaauuucaagaag
cugcuuugaguguagacgaucggucuaaguuccuuggaacaggacgucag
agagggugagaaccccgucuuuggucgauuggauaugccauauaaagcgc
uuucgaagagucgaguuguuugcagcucuaaauggguggucaucuaaagc
uaaauauuggcgagagaccgauagcgaacaaguagagugaucgaaagaug
aaaagaacuuugaaaagagaguuaaauaguacgugaaauugcugaaaggg
aagcauuggaaaucagucuuaccugggugagaucaguagucucucgagac
uaugcacucugaaccugugguaggucagcaucaguuuucgggggcggaaa
aagaauaagggaagguggcuguuuauagcccuuguuguaauacguccacu
ggggacugaggacugcggcuugccaaggaugcugacauaaugguuuucaa
uggcccgucuugaaacacggaccaaggagucuagcaucuaugcgaguguu
ugggugaugaaaacccauccgcgaagugggaacgcccuuguggcgugcac
caucagagcauagcuguugggacccgaaagauggugaaccaucuaguagc
ugguuccugccgaaguuuccggauagcagaaacucagaucaguuuuauga
guauguaaaaugagaguuucuagugggccauuuuugguaagcagaacugg
cgaugcgggaugaaccgaacgugagguuaaggugccggaauguacgcuca
ucagacgaaaagguguuaguucauaugaacuagcccugggcgcuuaagcg
uacuacccauaccucaccgucuggguuagcuuugagaagcucagacgagu
aggcaggcguggagguuugugacgaagccuugggcgugagccugggucga
acagccucuagugcagaucuugguggaaguagcuagaucuagcgaaacca
cagccuggggaacgggccaggcucauaccgaagcagaauucgguaagcuc
gucgcaaugguaauucaacuuaguacgagaggaaccguugauucagauca
uugguauuugcggccgcggagcuaucaucugccggauaacggcugaacgc
cucuaagccagaauccgugccagaaagcgacgauuauguauaaaaauaga
gguaggcuacucuccuguaucguagaagaugggcgaugguugaugaaacg
gaaguguuuuauugacuuguccaugaaauuccaugaauccauugcauacg
acuuuaauguggaacgggguauuguagauuaagccuuuguucccaagauu
ug
........................<<<<<<........>>>>>.>.....
....<<....>>..<<<<<......<<.>>.....>>>>>..<<<..<<.
......<<.<<<<<<<.......>>>>>>>.>>.......>>....<<<<
<.<<<<<..<<<<<..<<<<<<<<<.....<<<<......>>>>.((...
...<<<.....))>>>......>>>>>>>>>..>>>>>.....>>>>>>>
>.>>........<<<<<<<..>>>>>>>.....<<<<<..>>>>>..>>>
..................................<<....>>........
.......<<<<....>>>>...............................
...<<<<<<<<<<<<.....<<<.<<<<.<<<.<<.<<<<<<<..>>>>>
>>>>...>>>..>>>>..>>>..<<<<<<<.<<<<<<<<<<<<<<<....
.....<<<<<<.................>>>>>>........>>>>>.>>
>>>>>>>>........<<<..>>>.....>>>>>>>....>>>>>>>>>>
>>..<<<<........>>>><<<<<<....<<<<<<.<<<<<<..<<<..
.<<<<.......>>>>...>>>...<<<<..<<<<<.....>>>>>...>
>>>....>>>>>>.>>>>>>..<<.<..<<<<<<<..>>>>>>>.....>
.>>..<<<<<<....<.<<..>>.><<<<<<<<<....<<<.<<<<<<<.
...>>>>>>>>>>.>>>>>>>.>>..<<<<.<<<<<.....>>>>>.>>>
>....<<<......>>>...<<<<<<<...<<<(((.....<<<<<<...
..<<......<<<.<<<<<<<<<..>>>>>>>>>>>>.))).>>...>>>
>>>.>>>...>>>>>>><<<<<<<<<............>>>>>>>>>...
.>>>>>>..<<<<<<<..<<......<<<<.<<<<....>>>>>>>>...
>>.>>>>>>>........>>>>>><<.....<<<<<..>>>>>....>>.
...<<<<<........>>>>>....<<<<<<<......>>>>>>>...<<
<<<<<..<<<<.<.<<<<<.................>>>>>.><<<<<..
..<<<....<<<..>>>...>>>...>>>>>.<<<<....<<<<......
.....>>>>....>>>>.>>>>....>>>>>>>......<<.......<<
<<..<..>..>>>>....>>........<<<<<....<<<<<<<<<<<<.
.....>>>>>>>>>>>>..>>>>>..........<<<<<.<.........
....>.....<<<<<<<<<.<<<...>>>....>>>>.>>>>>...>>>>
>.
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8ev3 Chromatin localization of nucleophosmin organizes ribosome biogenesis.
Resolution3.0 Å
Binding residue
(original residue number in PDB)		A23 A66 L116 G117 E118 R119 I120 S153 A157 D169
Binding residue
(residue number reindexed from 1)		A20 A63 L113 G114 E115 R116 I117 S150 A154 D166
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0002181 cytoplasmic translation
GO:0006412 translation
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8ev3, PDBe:8ev3, PDBj:8ev3
PDBsum8ev3
PubMed36423630
UniProtQ10232|RL9A_SCHPO Large ribosomal subunit protein uL6A (Gene Name=rpl901)

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