Structure of PDB 7wn3 Chain H Binding Site BS01

Receptor Information
>7wn3 Chain H (length=478) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SLSCRPPMVKLVCPADNLRAEGLECTKTCQNYDLECMSMGCVSGCLCPPG
MVRHENRCVALERCPCFHQGKEYAPGETVKIGCNTCVCQDRKWNCTDHVC
DATCSTIGMAHYLTFDGLKYLFPGECQYVLVQDYCGSNPGTFRILVGNKG
CSHPSVKCKKRVTILVEGGEIELFDGEVNVKRPMKDETHFEVVESGRYII
LLLGKALSVVWDRHLSISVVLKQTYQEKVCGLCGNFDGIQNNDLTSSNLQ
VEEDPVDFGNSWKVSSQCADTRKVPLDSSPATCHNNIMKQTMVDSSCRIL
TSDVFQDCNKLVDPEPYLDVCIYDTCSCESIGDCACFCDTIAAYAHVCAQ
HGKVVTWRTATLCPQSCEERNLMENGYECMWRYNSCAPACQVTCQHPEPL
ACPVQCVEGCHAHCPPGKILDELLQTCVDPEDCPVCEVAGRRFASGKKVT
LNPSDPEHCQICHCDVVNLTCEACQEPG
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain7wn3 Chain H Residue 1302 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7wn3 Structural mechanism of VWF D'D3 dimer formation.
Resolution3.29 Å
Binding residue
(original residue number in PDB)		D879 N998 D1000 I1002 N1005 D1006
Binding residue
(residue number reindexed from 1)		D116 N235 D237 I239 N242 D243
Annotation score4
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:7wn3, PDBe:7wn3, PDBj:7wn3
PDBsum7wn3
PubMed35169124
UniProtP04275|VWF_HUMAN von Willebrand factor (Gene Name=VWF)

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