Structure of PDB 7v2p Chain H Binding Site BS01

Receptor Information
>7v2p Chain H (length=138) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MLTDPIADMLTRIRNATRVYKESTDVPASRFKEEILRILAREGFIKGYER
VDVDGKPYLRVYLKYGPRRQGPDPRPEQVIHHIRRISKPGRRVYVGVKEI
PRVRRGLGIAILSTSKGVLTDREARKLGVGGELICEVW
Ligand information
>7v2p Chain A (length=1394) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uggagaguuugauccuggcucagggugaacgcuggcggcgugccuaagac
augcaagucgugcgggccgcgggguuuuacuccguggucagcggcggacg
ggugaguaacgcgugggugaccuacccggaagagggggacaacccgggga
aacucgggcuaaucccccauguggacccgccccuugggguguguccaaag
ggcuuugcccgcuuccggaugggcccgcgucccaucagcuaguugguggg
guaauggcccaccaaggcgacgacggguagccggucugagaggauggccg
gccacaggggcacugagacacgggccccacuccuacgggaggcagcaguu
aggaaucuuccgcaaugggcgcaagccugacggagcgacgccgcuuggag
gaagaagcccuucgggguguaaacuccugaacccgggacgaaacccccga
cgaggggacugacgguaccgggguaauagcgccggccaacuccgugccag
cagccgcgguaauacggagggcgcgagcguuacccggauucacugggcgu
aaagggcguguaggcggccuggggcgucccaugugaaagaccacggcuca
accgugggggagcgugggauacgcucaggcuagacggugggagagggugg
uggaauucccggaguagcggugaaaugcgcagauaccgggaggaacgccg
auggcgaaggcagccaccugguccacccgugacgcugaggcgcgaaagcg
uggggagcaaaccggauuacccggguaguccacgcccuaaacgaugcgcg
cuaggucucugggucuccugggggccgaagcuaacgcguuaagcgcgccg
ccuggggaguacggccgcaaggcugaaacucaaaggaauugacgggggcc
cgcacaagcgguggagcaugugguuuaauucgaagcaacgcgaagaaccu
uaccaggccuugacaugcuagggaacccgggugaaagccuggggugcccc
gcgaggggagcccuagcacaggugcugcauggccgucgucagcucgugcc
gugagguguuggguuaagucccgcaacgagcgcaacccccgccguuaguu
gccagcgguucggccgggcacucuaacgggacugcccgcgaaagcgggag
gaaggaggggacgacgucuggucagcauggcccuuacggccugggcgaca
cacgugcuacaaugcccacuacaaagcgaugccacccggcaacggggagc
uaaucgcaaaaaggugggcccaguucggauuggggucugcaacccgaccc
caugaagccggaaucgcuaguaaucgcggaucagccaugccgcggugaau
acguucccgggccuuguacaagcuguaccggaaggugcggcugg
....<<<<..[.((((.>>>>.<<<<.<<<<<..<<<<<<<<..<..<<<
.<<<..<<<..<<.<<<<<<<<<<.....>>>>>>>>>>.>>>>>.....
.<<.......<<<<<<<<..<<...<<<<<<<.<<<<<....<<<<<<..
..>>>>>>.....>>>>>...<<<<<.<<<<<....>>>>>.>>>>>..<
<<<...>>>>.>>>>>>>..>>>>>>>>>><<<....<<<..<<<<<<<<
.......>>>>>>>>>>>......>>>..<<<<<<<<....>>>>...>>
>>.>>.<<<<<.<.........>>>>>>.<<<<....>>>>...>>>>>>
>........<<<....<<<<....>>>>..>>>..>>.>>>>>>..<<<<
......<<<<<..>>>>>.....>>>>....<<<<<........<<<<..
...>>>>..........>>>>>......<<<<<(((...<<<<<.....<
<.)))>>.......>>>>>>>>>>..>>>>>>>>>..........<<<((
.....<<<<...<<<.<<<<<<<.<<<<<<<<<<......<<<<<<....
.>>>>>>....>>>>>>>>..>>>>>>>>>...<<<<<<<<...<<<<<<
<....<<<<<<<.<..<<<......>>>.....>.>>>>>>>........
...<<....>>.>>>>>>>..>>>>>.>>>...>>>...>>>>....<<<
<<<...<<...<<<<.....>>>>...>>>>>>>>..........<<<<<
<..<<<<<<<<<<...>>>>>>>>>>...<<..))>>.....>>>>>>.>
>>.<<<......<<<<....>>>>....>>>..)))).]..<<<.<<<<<
<<.<<.<<<<<<..<<<<<<<<<<......<<........>>........
..<<<<<<<......<<<<<.<<..<<<<<<<....>>>>>>>...<<<<
....>>>>...>>>>>>>.<<<.<<<..<<<<<<<......<<<<<<<<<
....>>>..<<<<......>>>>..>>>>>>.....<<<<.<<<<<<<..
<<<..<<<.....>>>>>>...>>>>>>>.....<<<<<....>>>>>..
......>>>>.......>.>>>...>>>>>>>>>...>>>>>>>...>>.
>>>>>>>>.....<<<<<<<.....<<<..<<..<<<<....>>>>..>>
....>>>.....>>>>>>>......<....<<<<<<<........>>>>>
>>....>.....>>>>>>....<<<<<<<..........>>>>>>>....
..>>...>>>>>>>>>>...<<<<<<<<<....>>>>>>>>>..
Receptor-Ligand Complex Structure
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PDB7v2p Decoding the Mechanism of Specific RNA Targeting by Ribosomal Methyltransferases.
Resolution3.3 Å
Binding residue
(original residue number in PDB)		M1 T3 T11 R12 R14 N15 R18 V19 S29 R30 K56 R75 K88 P89 R91 R92 Y94 G96 V97 S113 T114 S115 G128 G130 E132
Binding residue
(residue number reindexed from 1)		M1 T3 T11 R12 R14 N15 R18 V19 S29 R30 K56 R75 K88 P89 R91 R92 Y94 G96 V97 S113 T114 S115 G128 G130 E132
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7v2p, PDBe:7v2p, PDBj:7v2p
PDBsum7v2p
PubMed35316014
UniProtP0DOY9|RS8_THET8 Small ribosomal subunit protein uS8 (Gene Name=rpsH)

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