Structure of PDB 7t7i Chain H Binding Site BS01

Receptor Information
>7t7i Chain H (length=241) Species: 10377 (Human herpesvirus 4 strain B95-8) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DRSHFSLRDFFRGISANFELGKDFLREMNTPIHVSEAVFLPLSLCTLSPG
RCLRLSPFGHSLTLGSHCEICINRSQVHVPQEFSSTQLSFFNNVHKIIPN
KTFYVSLLSSSPSAVKAGLSQPSLLYAYLVTGHFCGTICPIFSTNGKGRL
IMHLLLQGTSLHIPETCLKLLCENIGPTYELAVDLVGDAFCIKVSPRDTV
YEKAVNVDEDAIYEAIKDLECGDELRLQIINYTQLILENKQ
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain7t7i Chain H Residue 401 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7t7i The nuclear egress complex of Epstein-Barr virus buds membranes through an oligomerization-driven mechanism.
Resolution3.97 Å
Binding residue
(original residue number in PDB)		C129 C145 C148 H239
Binding residue
(residue number reindexed from 1)		C52 C68 C71 H162
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0046765 viral budding from nuclear membrane
GO:0046802 exit of virus from host cell nucleus by nuclear egress

View graph for
Biological Process
External links
PDB RCSB:7t7i, PDBe:7t7i, PDBj:7t7i
PDBsum7t7i
PubMed35802751
UniProtP0CK47|NEC1_EBVB9 Nuclear egress protein 1 (Gene Name=NEC1)

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