Structure of PDB 7sp1 Chain H Binding Site BS01

Receptor Information
>7sp1 Chain H (length=36) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EIVYKSPVVSGDTSPRHLSNVSSTGSIDMVDSPQLA
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7sp1 Cryo-EM structure of RNA-induced tau fibrils reveals a small C-terminal core that may nucleate fibril formation.
Resolution3.4 Å
Binding residue
(original residue number in PDB)
R406 H407 P423
Binding residue
(residue number reindexed from 1)
R16 H17 P33
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0008017 microtubule binding
GO:0015631 tubulin binding

View graph for
Molecular Function
External links
PDB RCSB:7sp1, PDBe:7sp1, PDBj:7sp1
PDBsum7sp1
PubMed35377792
UniProtP10636|TAU_HUMAN Microtubule-associated protein tau (Gene Name=MAPT)

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