Structure of PDB 7snq Chain H Binding Site BS01

Receptor Information
>7snq Chain H (length=209) Species: 11678 (Human immunodeficiency virus type 1 BH10) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PIVQNLQGQMVHQCISPRTLNAWVKVVEEKAFSPEVIPMFSALSCGATPQ
DLNTMLNTVGGHQAAMQMLKETINEEAAEWDRLHPVREPRGSDIAGTTST
LQEQIGWMTHNPPIPVGEIYKRWIILGLNKIVRMYSPTSILDIRQGPKEP
FRDYVDRFYKTLRAEQASQEVKNAATETLLVQNANPDCKTILKALGPGAT
LEEMMTACQ
Ligand information
>7snq Chain T (length=14) Species: 11676 (Human immunodeficiency virus 1) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
PVLFPGQPFGQPPL
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7snq Prion-like low complexity regions enable avid virus-host interactions during HIV-1 infection.
Resolution2.81 Å
Binding residue
(original residue number in PDB)		N53 L56 N57 Q67 K70 I73 N74 T107
Binding residue
(residue number reindexed from 1)		N53 L56 N57 Q67 K70 I73 N74 T97
Enzymatic activity
Enzyme Commision number 2.7.7.-
2.7.7.49: RNA-directed DNA polymerase.
2.7.7.7: DNA-directed DNA polymerase.
3.1.-.-
3.1.13.2: exoribonuclease H.
3.1.26.13: retroviral ribonuclease H.
3.4.23.16: HIV-1 retropepsin.
Gene Ontology

View graph for
Biological Process
External links
PDB RCSB:7snq, PDBe:7snq, PDBj:7snq
PDBsum7snq
PubMed36202818
UniProtP03366|POL_HV1B1 Gag-Pol polyprotein (Gene Name=gag-pol)

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