Structure of PDB 7s78 Chain H Binding Site BS01

Receptor Information
>7s78 Chain H (length=933) Species: 28285 (Human adenovirus 5) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MATPSMMPQWSYMHISGQDASEYLSPGLVQFARATETYFSLNNKFRNPTV
APTHDVTTDRSQRLTLRFIPVDREDTAYSYKARFTLAVGDNRVLDMASTY
FDIRGVLDRGPTFKPYSGTAYNALAPKGAPNPCEWDEAATALAEQQKTHV
FGQAPYSGINITKEGIQIGVEGQTPKYADKTFQPEPQIGESQWYETEINH
AAGRVLKKTTPMKPCYGSYAKPTNENGGQGILVKQQNGKLESQVEMQFFS
TTEATAGNGDNLTPKVVLYSEDVDIETPDTHISYMPTIKEGNSRELMGQQ
SMPNRPNYIAFRDNFIGLMYYNSTGNMGVLAGQASQLNAVVDLQDRNTEL
SYQLLLDSIGDRTRYFSMWNQAVDSYDPDVRIIENHGTEDELPNYCFPLG
GVINTETLTKVKPKTGQENGWEKDATEFSDKNEIRVGNNFAMEINLNANL
WRNFLYSNIALYLPDKLKYSPSNVKISDNPNTYDYMNKRVVAPGLVDCYI
NLGARWSLDYMDNVNPFNHHRNAGLRYRSMLLGNGRYVPFHIQVPQKFFA
IKNLLLLPGSYTYEWNFRKDVNMVLQSSLGNDLRVDGASIKFDSICLYAT
FFPMAHNTASTLEAMLRNDTNDQSFNDYLSAANMLYPIPANATNVPISIP
SRNWAAFRGWAFTRLKTKETPSLGSGYDPYYTYSGSIPYLDGTFYLNHTF
KKVAITFDSSVSWPGNDRLLTPNEFEIKRSVDGEGYNVAQCNMTKDWFLV
QMLANYNIGYQGFYIPESYKDRMYSFFRNFQPMSRQVVDDTKYKDYQQVG
ILHQHNNSGFVGYLAPTMREGQAYPANFPYPLIGKTAVDSITQKKFLCDR
TLWRIPFSSNFMSMGALTDLGQNLLYANSAHALDMTFEVDPMDEPTLLYV
LFEVFDVVRVHRPHRGVIETVYLRTPFSAGNAT
Ligand information
>7s78 Chain 2 (length=19) Species: 28285 (Human adenovirus 5) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
NFASLAPRHGSNMSGGAFS
Receptor-Ligand Complex Structure
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PDB7s78 Structure of a Cell Entry Defective Human Adenovirus Provides Insights into Precursor Proteins and Capsid Maturation.
Resolution3.72 Å
Binding residue
(original residue number in PDB)
F30 A33 T36 Y37
Binding residue
(residue number reindexed from 1)
F31 A34 T37 Y38
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005198 structural molecule activity
Biological Process
GO:0046718 symbiont entry into host cell
GO:0075521 microtubule-dependent intracellular transport of viral material towards nucleus
Cellular Component
GO:0019028 viral capsid
GO:0039623 T=25 icosahedral viral capsid
GO:0042025 host cell nucleus
GO:0043657 host cell

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:7s78, PDBe:7s78, PDBj:7s78
PDBsum7s78
PubMed34774568
UniProtP04133|CAPSH_ADE05 Hexon protein (Gene Name=L3)

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