Structure of PDB 7oqc Chain H Binding Site BS01

Receptor Information
>7oqc Chain H (length=192) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MSTPAAEQRKLVEQLMGLHDPKICKSYLVGECPYDLFQGTKQSLGKCPQM
HLTKHKIQYEREVKQGKTFPEFEREYLAILSRFVNECNGQISVALQNLKH
TAEERMKIQQVTEELDVLDLISKRKEVAKRVRNITENVGQSAQQKLQVCE
VCGAYLSRLDTDRRLADHFLGKIHLGYVKMREDYDRLMKNNR
Ligand information
>7oqc Chain 1 (length=558) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
auacuuaccuuaagauaucagaggagaguccuacugaucaaacaugcgcu
uccaauaguagaaggacguuaagcauuuaucauugaacuauaauuguuca
uugaagucauugaugcaaacuccuuggucacacacacauacggcgcggaa
ggcguguuugcugacguuuccauucccuuguuucaaucauugguuaaucc
cuugauuccuuuggggauuuuuggguuaaacugauuuuuggggcccuuug
uuucuucugccuggagaaguuugacaccaaauucaaauugguguuagggg
agcuggggccuuucaaaagagagcuuuguagaggcauucuuuuugacuac
uuuucucuagcgugccauuuuaguuuuugacggcagauucgaaugaacuu
aaguuuaugaugaagguauggcuguugagauuauuuggucgggauuguag
uuugaagaugugcucuuuugagcagucucaacuuugcucguucccguuau
gggaaaaauuuuggaaggucuugguaggaacggguggaucuuauaauuuu
ugauuuau
...........<<<<.<<<<<<<<<...>>>>.>>>>><<<<<<<<<.<<
<<<........<<<<<.<<<..<<<<.<.<<<.<<<<<.......>>>>>
.>>>.......>>>>>.>>>>>>>>.....................>>>>
>>>>>>>>>><<<.<<<<.<<..<<<<<.<<<<<<<..<<<<<<<.<.<<
<..<<<<<<<..>>>>>>>...>>>.>.>>>>>>>..>>>>>>>((....
...<<<<<....))>>>>>...<<<<<<<<.......>>>>>>>>.>>>>
><<<<<<<<<<<<<<<<<..<<<<...<<.<<<<...<<<<<..<<<<<<
..<<<<.......<<<<...<<<<<<<.<<<<<<...<<<<.<<<<<<..
..>>>>>>..>>>>......>>>>>>>>>>>>>..>>>>.>>>>..>>>>
>>.>>>>>..<<<<<....>>>>>.>>>>.>>...>>>>.<<<<<<...>
>>>>>...>>>>>>>>>>>>>>>>>.>>>>>>..>>>.>>>>........
........
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB7oqc Structural insights into how Prp5 proofreads the pre-mRNA branch site.
Resolution4.1 Å
Binding residue
(original residue number in PDB)
S5 T6 Y207 R216 H220 G223 K224
Binding residue
(residue number reindexed from 1)
S2 T3 Y155 R164 H168 G171 K172
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003729 mRNA binding
GO:0008270 zinc ion binding
Biological Process
GO:0000395 mRNA 5'-splice site recognition
GO:0000398 mRNA splicing, via spliceosome
GO:0006376 mRNA splice site recognition
GO:0006397 mRNA processing
GO:0008380 RNA splicing
Cellular Component
GO:0000243 commitment complex
GO:0005634 nucleus
GO:0005681 spliceosomal complex
GO:0005685 U1 snRNP
GO:0005829 cytosol
GO:0071004 U2-type prespliceosome

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:7oqc, PDBe:7oqc, PDBj:7oqc
PDBsum7oqc
PubMed34349264
UniProtQ07508|LUC7_YEAST Protein LUC7 (Gene Name=LUC7)

[Back to BioLiP]