Structure of PDB 7ohu Chain H Binding Site BS01

Receptor Information
>7ohu Chain H (length=190) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MKYIQTEQQIEVPEGVTVSIKSRIVKVVGPRGTLTKNLKHIDVTFTKVNN
QLIKVAVHNGGRKHVAALRTVKSLVDNMITGVTKGYKYKMRYVYAHFPIN
VNIVEKDGAKFIEVRNFLGDKKIRNVPVRDGVTIEFSTNVKDEIVLSGNS
VEDVSQNAADLQQICRVRNKDIRKFLDGIYVSHKGFITED
Ligand information
>7ohu Chain 1 (length=1692) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
guuugaccucaaaucagguaggaguacccgcugaacuuauaucaauaagc
ggaggaaaagaaaccaaccgggauugccuuaguaacggcgagugaagcgg
caaaagcucaaauuugaaaucugguaccuucggugcccgaguuguaauuu
ggagagggcacuuuggggccguuccuugucuauguuccuuggaacaggac
gucauagagggugagaaucccguguggcgaggagugcgguucuuuguaaa
gugccuucgaagagucgaguuguuugggaaugcagcucuaaguggguggu
uccaucuaaagcuaaauauuggcgagagaccgauagcgaacaaguacagu
gauggaaagaugaaaagaacuuugaaaagagagugaaaaaguacgugaaa
uuguugaaagggaagggcauuugaucagacaugguguuuuguggggaauc
ucgcauuucacugggccagcaucaguuuugguggcaggauaaauccauag
gaauguagcuugccucgguaaguauuauagccugugggaauacugccagc
ugggacugaggacugcgacguaagucaaggaugcuggcauaaugguuaua
ugccgccgucuugaaacacggaccaagggucuaacgucuaugcgaguguu
uggguguaaaacccauacgcguaaugaaagugaacguagguuggggccuc
gcaagaggugcacaaucgaccgauccugaggauggauuugaguaagagca
uagcuguugggacccgaaagauggugaaaccaucuaguacugguuccugc
cgaaguuucccucaggauagcagaagcucguaucaguuuuauuaaaauga
agagcuuuuagugggccauuuuugguaagcagaacuggcgaugcgggaug
aaccgaacguagaguuaaggugccggaauacacgcucaucagaccaaaag
guguuaguucaucuagacagccggacgguggccauggaagucggaauccg
cuaaggaguguguaacaacucaccggccgaaugaacuagcccugaauggc
gcucaagcguguuaccuauacucuaccgucaggguugauaugaugcccug
acgaguaggcaggcguggaggucagugacgaagccuagaccguaaggucg
ggucgaacggccucuagugagaucuuggugguaguagcagcgaaaccaca
gccaagggacgggcuuggcagaaucagcgggggcuuguggcagucaagcg
gcgacauugcucauaccgaagcagaauucgguaagcgucuacugaugaug
uuaccgcaauaguaauugaacuuaguacgagaggaacaguucauucggau
aauugguuuuugcggcugucugaucaggcagccgcgaagcuaccauccgc
uggauuauggcugaacgccucuaagucagauccaugcuagaacgcgguga
uuucuuugcuccacacaauauagauggauacgaauaaggcguccuugugg
cgucgcugaaccauagcaggcuagcaacggugcacuuggcggaaaggccu
ugggugcuugcuggcgaauugcaaugucauuuugcguggggauaaaucau
uuguauacgacuuagauguacaacgggguauuguaagcaguagaguagcc
ugguuacgaucugcugagauuaaccuuuguugucugauuugu
..........................<<<<<<...............>>>
>>.>.........<<....>>..<<<<<......<<.....>>.....>>
>>>..<<<..<........<<.<<<<<<...>>>>>>.>>........>.
...<<<<<<<<<<..<<<<<<<<<<<<<<<.....<<<<......>>>>.
((......<<<.....))>>>....>>>>>>>>..>>>>>>>......>>
>>>>>>>>........<<<<<<<........>>>>>>>.....<<<<<<.
.>>>>>>..>>>..................................<<..
..>>...............<<<<....>>>>...................
...............<<<<<.<<<<<.<....<<<<...<<<........
..>>>...>>>>..<<<<<<<.<<<<<<<<<<<<<<<.....<<<<<<<<
<......<<<<<......>>>>>.......>>>>>>>.>.>.>>>>>.>>
>>>>>>>>........<<<....>>>.....>>>>>>>....>>>>>>.>
>>>>.<<<<........>>>><<<<<<...<<<<<<.<<<<<<..<<<..
.<<<<.....>>>>...>>>..................<<<<<..<<<<<
....>>>>>...>>>>>.<<<<<<<<.......>>>.>>>.>>....>>>
>>>.>>>>>>..<<.<...<<<<<<...>>>>>>.....>.>>..<<<<<
<....<.<<......>>.><<<<<<<<<....<<<.<<<<...>>>>>>>
..>>>>>>>.>>..<<<<.<<<<<.....>>>>>.>>>>....<<<....
..>>>...<<<<<<<..<<<<(((.....<<<<<<......<......<<
<.<<<<<<<<<<.......<<<<<.<<....<<.........>>....>>
.........<<......>>...>>>>>...>>>>>>>>>>>>>....)))
.>....>>>>>>.>>>>..>>>>>>><<<<<<<<<.........>>>>>>
>>>....>>>>>><.<<<<<<<<.<<......<<<<.<<<<....>>>>>
>>>...>>>>>>>>>>..>....>>>>>><<.....<<.>>....>>...
.<<<<<.......>>>>>....<<<<<..<.........<<<<....<<.
>>....>>>>...<<<<<<<......>>>>>>>......>.>>>>>...<
<<<<<<<..<<<<.<.<<<<<<...............>>>>>>.><<<<<
...<<......<<<<<<<<........>>>>>>>>.....>>..>>>>>.
<<<<...<<<<<...........>>>>>..>>>>.>>>>....>>>>>>>
>.......<<<<<<.<<<.<<....<<..........<<<<<<.....>>
>>>>......>>.......<<<<<<...<<<<<.<..<<<......>>>.
.>.>>>>>.>>>>>>.............>>.>>>.>>>>>>..<<<<<.<
.............>.....<<<<<<<<<.<<<....<<<<....<<.<<.
..>>.>>...>>>>...>>>...>>>>.>>>>>..>>>>>..
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7ohu Analysis of subunit folding contribution of three yeast large ribosomal subunit proteins required for stabilisation and processing of intermediate nuclear rRNA precursors.
Resolution3.7 Å
Binding residue
(original residue number in PDB)
M1 S19 K21 S22 R23 I24 K26 H40 D42 V43 T44 V57 H58 R62 A66 R69 T70 S73 L74 N77 H96 F97 D120 K121 K122 V151 E152 S155 Q156 Q163 R168 K170 D171 R173 K174
Binding residue
(residue number reindexed from 1)
M1 S19 K21 S22 R23 I24 K26 H40 D42 V43 T44 V57 H58 R62 A66 R69 T70 S73 L74 N77 H96 F97 D120 K121 K122 V151 E152 S155 Q156 Q163 R168 K170 D171 R173 K174
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0002181 cytoplasmic translation
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:7ohu, PDBe:7ohu, PDBj:7ohu
PDBsum7ohu
PubMed34813592
UniProtP05738|RL9A_YEAST Large ribosomal subunit protein uL6A (Gene Name=RPL9A)

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