Structure of PDB 7jm4 Chain H Binding Site BS01

Receptor Information
>7jm4 Chain H (length=108) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NGKLRQWLIDQIDSGKYPGLVWENEEKSIFRIPWKHAGKQDYNREEDAAL
FKAWALFKGKFREGIDKPDPPTWKTRLRCALNKSNDFEELVERSQLDISD
PYKVYRIV
Ligand information
Receptor-Ligand Complex Structure
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PDB7jm4 Structural determinants of the IRF4/DNA homodimeric complex.
Resolution2.95 Å
Binding residue
(original residue number in PDB)		W54 H56 A57 K59 Q60 Y62 K94 R98 N102 K103
Binding residue
(residue number reindexed from 1)		W34 H36 A37 K39 Q40 Y42 K74 R78 N82 K83
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000976 transcription cis-regulatory region binding
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:7jm4, PDBe:7jm4, PDBj:7jm4
PDBsum7jm4
PubMed33533913
UniProtQ15306|IRF4_HUMAN Interferon regulatory factor 4 (Gene Name=IRF4)

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