Structure of PDB 6yam Chain H Binding Site BS01

Receptor Information
>6yam Chain H (length=191) Species: 9986 (Oryctolagus cuniculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TPDIKLFGKWSTDDVQINDISLQDYIAVKEKYAKYLPHSAGRYAAKRFRK
AQCPIVERLTNSMMMHGRNNGKKLMTVRIVKHAFEIIHLLTGENPLQVLV
NAIINSGPREDSTRIGRAGTVRRQAVDVSPLRRVNQAIWLLCTGAREAAF
RNIKTIAECLADELINAAKGSSNSYAIKKKDELERVAKSNR
Ligand information
>6yam Chain 2 (length=1743) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uaccugguugauccugccaguagcauaugcuugucucaaagauuaagcca
ugcaugucuaaguacgcacggccgguacagugaaacugcgaauggcucau
uaaaucaguuaugguuccuuuggucgcuacuuggauaacugugguaauuc
uagagcuaauacaugccgacggcgcugacucccuuugugugggaugcgug
cauuuaucagaucaaaaccaacccggucggcggcuuuggugacucuagau
aaccucgggccgaucgcagcccuccguggcggcgacgacccauucgaacg
ucugcccuaucaacuuucgaugguagucgccgugccuaccauggugacca
cgggugacggggaaucaggguucgauuccggagagggagccugagaaacg
gcuaccacauccaaggaaggcagcaggcgcgcaaauuacccacucccgac
ccggggagguagugacgaaaaauaacaauacaggacucuuucgaggcccu
guaauuggaaugaguccacuuuaaauccuuuaacgaggauccauuggagg
gcaagucuggucgcagcagccgcgguaauuccagcuccaauagcguauau
uaaaguugcugcaguuaaaaagcucguaguuggaucuuguggaggguucc
ccgccccuugccucucggcgccggcccgaagcguuuacuuugaaaaaauu
agaguguucaaagcaggcccgagccgccuggauaccgcagcuaggaauaa
uggaauaggaccgcgguucuauuuuguugguuuucggaacugaggccaug
auuaagagggacggccgggggcauucguauugcgccgcuagaggugaaau
ucuuggaccggcgcaagacggaccagagcgaaagcauuugccaagaaugu
uuucauuaaucaagaacgaaagucggagguucgaagacgaucagauaccg
ucguaguuccgaccauaaacgaugccgacuggcgaugcggcggcguuauu
cccaugacccgccgggcagcuuccgggaaaccaaagucuuuggguuccgg
ggggaguaugguugcaaagcugaaacuuaaaggaauugacggaagggcac
caccaggaguggagccugcggcuuaauuugacucaacacgggaaaccuca
cccggcccggacacggacaggauugacagauugauagcucuuucucgauu
cugugggugguggugcauggccguucuuaguugguggagcgauuugucug
guuaauuccgauaacgaacgagacucuggcaugcuaacuaguuacgcgac
ccccgagcggucggcgucccccaacuucuuagagggacaaguggcguuca
gccacccgagauugagcaauaacaggucugugaugcccuuagaugucggg
gcugcacgcgcgcuacacugacuggcucagcgugugccuacccuacgccg
gcaggcgcggguaacccguugaaccccauucgugauggggaucggggauu
gcaauuauuccccaugaacgaggaauucccaguaagugcgggucauaagc
uugcguugauuaagucccugcccuuuguacacaccgcccgucgcuacuac
cgauuggaugguuuagugaggcccucggaucggcccgccggggugcccug
gcggagcgcugagaagacggucgaacuugacuaucuagaggaaguaaaag
ucguaacaagguuuccguaggugaaccugcggaaggaucauua
...<<<<<...[[[[>>>>>[[[.((((((.....{{.........[[[.
[[[..<<....<<....<<..........>>...>>.>>......{{...
.....[[[......{{....[[[........<<.....<<.<<<.....>
>>.>>......>>.........<<<...<<.<......>.>>...>>>.[
[..(((((.....<<<<<<<<<<<<.....>>>....<......>..)))
))......]]...<<<<.<<<......>>>.>>>>....]]]...}}...
.]]].<<<....<<<....<<<<<<<.........>>>>>>>>>>.....
.>>>...<<<.<<<<....>>>>....>>>.}}.<<.<<<..........
>>>.>>.<.<<....>>.>...]]]]]].........<<<....<<<<..
.>>>>..>>>......}}.......<<<<<<.<<.<<<....>>>.>>..
>>>.>>>......<<..<...........>..>>.........<<<<<((
......<<<<.....<<..))>>.......>>>>.>>>>>..)))))).]
]]............{{.......{{...[[[.[[....<<<<.<<...>>
>>>>........<......<<..>>....>....<<<<<<.<.......<
<...<.......>.<<<<.......>>>>...>>......>.>>>..>>>
.......[[....(((((((.....>>>>>>>>>.)))))))...]]...
.]]....<<<<<<..<...<<<<..<<..<<<<<<<<...<<<......>
>>......>>>>>>>>..>>.......<<....>>...>>>>..>..>>>
.>>>...]]]...}}......<<<<<<<...<...<<<<.<.....>.>>
>>...>>>>>>>>..........<<<.<<.<<<..<.<<<<<<.<<<<..
....>>>>>>>>>>.>..>>>...<<..}}>>...>>.....>>>.....
<<<......<<<<....>>>>....>>>..]]]]..<<<<<.<<<<<<<.
.<<..<<<<<..<<<.<<<<<<......<<........>>..........
<<<<<......<<<<<<.......<<.<<<........>>>.>>.....>
>>>>>...<<.<<<..<<<<<<<<<....<<<.<<<<<....>>>...<<
<......>>>...>>.>>>....<<<...<...<<<<..<<<<....<<<
..<<<<....>>>>.>>>....>>>>..>>>>..>.....<<<<<.....
>>>>>........>>>....>>>.>>>...>.>>>>>>>......>>>>>
...>>.>>>>.>>>.....<<.<<<........<.......<<<.<<<<.
...>>>>.>>>....>.........>>>.>>......<.....<<<<<..
........>>>>>.....>.....>>>>>.....<<<<<<<<.......>
>>>>>>>......>>...>>>>>>>>>>.>>....<..<<.<..<<<<.<
<....<<<<<<<<.<<<..<<<<.<<...<<<<<.<<<<<<<<..>>>>>
>>.>...>>>>>...>>.>>>>..>>>.>>>>>>>>...>>.>>>>...>
.>>...>.....<<<<<<<<<<..>>>>>>>>>>.........
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6yam Structural Insights into the Mammalian Late-Stage Initiation Complexes.
Resolution3.6 Å
Binding residue
(original residue number in PDB)		Y56 A58 K59 R60 K63 N74 M76 M78 H79 G80 R81 N82 G84 M88 N148 W152 R159 F163 R164 N165 I166 T168 I169
Binding residue
(residue number reindexed from 1)		Y43 A45 K46 R47 K50 N61 M63 M65 H66 G67 R68 N69 G71 M75 N135 W139 R146 F150 R151 N152 I153 T155 I156
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0015935 small ribosomal subunit

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6yam, PDBe:6yam, PDBj:6yam
PDBsum6yam
PubMed
UniProtU3KMN4

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