Structure of PDB 6w9d Chain H Binding Site BS01

Receptor Information
>6w9d Chain H (length=67) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PRGLTKEQIDNLAMRSFDALKTCSVCITEYTEGNKLRKLPCSHEYHVHCI
DRWLSENSTCPICRRAV
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain6w9d Chain H Residue 701 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB6w9d The RING Domain of RING Finger 12 Efficiently Builds Degradative Ubiquitin Chains.
Resolution3.19 Å
Binding residue
(original residue number in PDB)		C570 C573 H593 C596
Binding residue
(residue number reindexed from 1)		C23 C26 H46 C49
Annotation score4
Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
External links
PDB RCSB:6w9d, PDBe:6w9d, PDBj:6w9d
PDBsum6w9d
PubMed32416094
UniProtQ9NVW2|RNF12_HUMAN E3 ubiquitin-protein ligase RLIM (Gene Name=RLIM)

[Back to BioLiP]