Structure of PDB 6vz8 Chain H Binding Site BS01

Receptor Information

>6vz8 Chain H (length=531) Species: 3702 (Arabidopsis thaliana) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

FISRFAPDQPRKGADILVEALERQGVETVFAYPGGASMEIHQALTRSSSI
RNVLPRHEQGGVFAAEGYARSSGKPGICIATSGPGATNLVSGLADALLDS
VPLVAITGQVPRRMIGTDAFQETPIVEVTRSITKHNYLVMDVEDIPRIIE
EAFFLATSGRPGPVLVDVPKDIQQQLAIPNWEQAMRLPGYMSRMPKPPED
SHLEQIVKPVLYVGGGCLNDELGRFVELTGIPVASTLMGLGSYPCDDELS
LHMLGMHGTVYANYAVEHSDLLLAFGVRFDDRVTGIVHIDIDSAEIGKNK
TPHVSVCGDVKLALQGMNKVLENRAEELKLDFGWRNELNVQKQKFPLSFG
EAIPPQYAIKVLDELTDGKAIISTGVGQHQMWAAQFYNYKKPRQWLSSGG
LGAMGFGLPAAIGASVANPDAIVVDIDGDGSFIMNVQELATIRVENLPVK
VLLLNNQHLGMVMQWEDRFYKANRAHTFLGDPAQIFPNMLLFAAACGIPA
ARVTKKADLREAIQTMLDTPGPYLLDVICPH

Ligand information

Ligand ID

InChI

InChI=1S/Mg/q+2

InChIKey

JLVVSXFLKOJNIY-UHFFFAOYSA-N

SMILES

Software	SMILES
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Mg+2]
CACTVS 3.341	[Mg++]

Formula

Name

MAGNESIUM ION

PDB chain

6vz8 Chain H Residue 701 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

Global view

Local view

Structure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

PDB	6vz8 Structures of fungal and plant acetohydroxyacid synthases.
Resolution	3.45 Å
Binding residue (original residue number in PDB)	H567 L568 G569
Binding residue (residue number reindexed from 1)	H458 L459 G460
Annotation score	1

Enzymatic activity

Catalytic site (original residue number in PDB)	Y118 G120 G121 A122 S123 E144 T167 F206 Q207 E208 K256 M351 V378 V485 G511 M513 D538 N565 H567 L568 M570 V571 W574
Catalytic site (residue number reindexed from 1)	Y32 G34 G35 A36 S37 E58 T81 F120 Q121 E122 K170 M256 V283 V376 G402 M404 D429 N456 H458 L459 M461 V462 W465
Enzyme Commision number	2.2.1.6: acetolactate synthase.

Gene Ontology

	Molecular Function
GO:0000287	magnesium ion binding
GO:0003824	catalytic activity
GO:0003984	acetolactate synthase activity
GO:0030976	thiamine pyrophosphate binding
GO:0050660	flavin adenine dinucleotide binding

	Biological Process
GO:0009082	branched-chain amino acid biosynthetic process

View graph for
Molecular Function

View graph for
Biological Process

External links

PDB	RCSB:6vz8, PDBe:6vz8, PDBj:6vz8
PDBsum	6vz8
PubMed	32640464
UniProt	P17597\|ILVB_ARATH Acetolactate synthase, chloroplastic (Gene Name=ALS)

[Back to BioLiP]