Structure of PDB 6upl Chain H Binding Site BS01

Receptor Information
>6upl Chain H (length=411) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MAETLEFNDVYQEVKGSMNDGRLRLSRQGIIFKNSKTGKVDNIQAGELTE
GIWRRHGLKLLTKNGHVYKYDGFRESEFEKLSDFFKTHYRLELMEKDLCV
KGWNWGTVKFGGQLLSFDIGDQPVFEIPLSNVSQCTTGKNEVTLEFHQND
DAEVSLMEVRFYVPPTQAAAAAAAAAAAAADAICIFRELQCLTPRGRYDI
RIYPTFLHLHGKTFDYKIPYTTVLRLFLLPHKDQRQMFFVISLDPPIKQG
QTRYHFLILLFSKDEDISLTLNMNEEEVEKRFEGRLTKNMSGSLYEMVSR
VMKALVNRKITVPGNFQGHSGAQCITCSYKASSGLLYPLERGFIYVHKPP
VHIRFDEISFVNFARGTTTTRSFDFEIETKQGTQYTFSSIEREEYGKLFD
FVNAKKLNIKN
Ligand information
>6upl Chain I (length=79) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
tcgtagacagctctagcaccgcttaaacgcacgtacgcgctgtcccccgc
gttttaaccgccaaggggattactcccta
Receptor-Ligand Complex Structure
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PDB6upl FACT caught in the act of manipulating the nucleosome.
Resolution7.4 Å
Binding residue
(original residue number in PDB)		R213 K228 T229
Binding residue
(residue number reindexed from 1)		R197 K212 T213
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003682 chromatin binding
GO:0003723 RNA binding
GO:0005515 protein binding
GO:0031491 nucleosome binding
GO:0042393 histone binding
Biological Process
GO:0006260 DNA replication
GO:0006281 DNA repair
GO:0006334 nucleosome assembly
GO:0006337 nucleosome disassembly
GO:1902275 regulation of chromatin organization
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005694 chromosome
GO:0005730 nucleolus
GO:0035101 FACT complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6upl, PDBe:6upl, PDBj:6upl
PDBsum6upl
PubMed31775157
UniProtQ08945|SSRP1_HUMAN FACT complex subunit SSRP1 (Gene Name=SSRP1)

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