Structure of PDB 6uoe Chain H Binding Site BS01

Receptor Information
>6uoe Chain H (length=225) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PVQLVESGGGVVQPGRSLRLSCAASGFTFSNHGLHWVRQAPGKGLEWVAV
VSKDGTNEHYADSVRGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCAREG
YCGDDRCYSGQPDYWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAAL
GCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSS
LGTQTYICNVNHKPSNTKVDKKVEP
Ligand information
>6uoe Chain P (length=12) Species: 10359 (Human betaherpesvirus 5) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
NETIYNTTLKYG
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6uoe Recognition of a highly conserved glycoprotein B epitope by a bivalent antibody neutralizing HCMV at a post-attachment step.
Resolution1.8 Å
Binding residue
(original residue number in PDB)		H32 S52 D53 N56 R94 G96 Y97 C98 R100B C100C Y100D S100E
Binding residue
(residue number reindexed from 1)		H32 S52 D54 N57 R98 G100 Y101 C102 R106 C107 Y108 S109
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:6uoe, PDBe:6uoe, PDBj:6uoe
PDBsum6uoe
PubMed32745149
UniProtP0DOX5|IGG1_HUMAN Immunoglobulin gamma-1 heavy chain

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