Structure of PDB 6uh5 Chain H Binding Site BS01

Receptor Information
>6uh5 Chain H (length=93) Species: 8355 (Xenopus laevis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TRKESYAIYVYKVLKQVHPDTGISSKAMSIMNSFVNDVFERIAGEASRLA
HYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTCYTSA
Ligand information
>6uh5 Chain I (length=146) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
tcgagaatcccggtgccgaggccgctcaattggtcgtagacagctctagc
accgcttaaacgcacgtacgcgctgtcccccgcgttttaaccgccaaggg
gattactccctagtctccaggcacgtgtcagatatatacatccgat
Receptor-Ligand Complex Structure
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PDB6uh5 Structural Basis of H2B Ubiquitination-Dependent H3K4 Methylation by COMPASS.
Resolution3.5 Å
Binding residue
(original residue number in PDB)
Y39 I51 S52 S84 T85
Binding residue
(residue number reindexed from 1)
Y11 I23 S24 S56 T57
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Cellular Component
GO:0000786 nucleosome
GO:0005634 nucleus
GO:0005694 chromosome

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Molecular Function

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Cellular Component
External links
PDB RCSB:6uh5, PDBe:6uh5, PDBj:6uh5
PDBsum6uh5
PubMed31733991
UniProtP02281|H2B11_XENLA Histone H2B 1.1

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