Structure of PDB 6ssp Chain H Binding Site BS01

Receptor Information
>6ssp Chain H (length=302) Species: 556 (Dickeya chrysanthemi) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RPVDVSVSIFINKIYGVNTLEQTYKVDGYIVAQWTGKPRKTPGDKPLIVE
NTQIERWINNGLWVPALEFINVVGSPDTGNKRLMLFPDGRVIYNARFLGS
FSNDMDFRLFPFDRQQFVLELEPFSYNNQQLRFSDIQVYTENIDNEEIDE
WWIRGKASTHISDIRYDHLPNQNEFSRITVRIDAVRNPSYYLWSFILPLG
LIIAASWSVFWLESFSERLQTSFTLMLTVVAYAFYTSNILPRLPYTTVID
QMIIAGYGSIFAAILLIIFAHHRQNVEDDLLIQRCRLAFPLGFLAIGCVL
VI
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain6ssp Chain H Residue 401 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6ssp Modulation of the Erwinia ligand-gated ion channel (ELIC) and the 5-HT 3 receptor via a common vestibule site.
Resolution3.25 Å
Binding residue
(original residue number in PDB)		N154 D158
Binding residue
(residue number reindexed from 1)		N145 D149
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0004888 transmembrane signaling receptor activity
GO:0005216 monoatomic ion channel activity
GO:0005230 extracellular ligand-gated monoatomic ion channel activity
Biological Process
GO:0006811 monoatomic ion transport
GO:0034220 monoatomic ion transmembrane transport
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6ssp, PDBe:6ssp, PDBj:6ssp
PDBsum6ssp
PubMed31990273
UniProtP0C7B7|ELIC_DICCH Cys-loop ligand-gated ion channel

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