Structure of PDB 6n9x Chain H Binding Site BS01

Receptor Information
>6n9x Chain H (length=645) Species: 10760 (Escherichia phage T7) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MIVSAIAANALLESVTKFHCGVIYDYSTAEYVSYRPSDFGAYLDALEAEV
ARGGLIVFHNGHKYDVPALTKLAKLQLNREFHLPRENCIDTLVLSRLIHS
NLKDTDMGLLRKLPGKRFGSHALEAWGYRLGEMKGEYKDDFKRMLEEQGE
EYVDGMEWWNFNEEMMDYNVQDVVVTKALLEKLLSDKHYFPPEIDFTDVG
YTTFWSESLEAVDIEHRAAWLLAKQERNGFPFDTKAIEELYVELAARRSE
LLRKLTETFGSWYQPKYTPVEHVVFNPSSRDHIQKKLQEAGWVPTKYTDK
GAPVVDDEVLEGVRVDDPEKQAAIDLIKEYLMIQKRIGQSAEGDKAWLRY
VAEDGKIHGSVNPNGAVTGRATHAFPNLAQIPGVRSPYGEQCRAAFGAEH
HLDGITGKPWVQAGIDASGLELRCLAHFMARFDNGEYAHEILNGDIHTKN
QIAAELPTRDNAKTFIYGFLYGAGDEKIGQIVGAGKERGKELKKKFLENT
PAIAALRESIQQTLVESSQWVAGEQQVKWKRRWIKGLDGRKVHVRSPHAA
LNTLLQSAGALICKLWIIKTEEMLVEKGLKHGWDGDFAYMAWVHDEIQVG
CRTEEIAQVVIETAQEAMRWVGDHWNFRCLLDTEGKMGPNWAICH
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB6n9x Structures and operating principles of the replisome.
Resolution4.1 Å
Binding residue
(original residue number in PDB)		R339 D366 K394 A438 Q439 I440 H653
Binding residue
(residue number reindexed from 1)		R280 D307 K335 A379 Q380 I381 H594
Enzymatic activity
Enzyme Commision number 2.7.7.7: DNA-directed DNA polymerase.
3.1.11.-
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0003887 DNA-directed DNA polymerase activity
GO:0004527 exonuclease activity
GO:0004529 DNA exonuclease activity
GO:0005515 protein binding
GO:0008408 3'-5' exonuclease activity
GO:0046872 metal ion binding
Biological Process
GO:0006260 DNA replication
GO:0006261 DNA-templated DNA replication
GO:0006302 double-strand break repair
GO:0039693 viral DNA genome replication
GO:0090592 DNA synthesis involved in DNA replication

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:6n9x, PDBe:6n9x, PDBj:6n9x
PDBsum6n9x
PubMed30679383
UniProtP00581|DPOL_BPT7 DNA-directed DNA polymerase (Gene Name=5)

[Back to BioLiP]