Structure of PDB 6dcw Chain H Binding Site BS01
Receptor Information
>6dcw Chain H (length=223) Species:
9606
(Homo sapiens) [
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QVQLVESGPEMRKPGESLKISCKTSGYIFSDYWTAWVRQLPGKGLQWMGI
IYSGDSDTRYHPSVQGHVTMSTDSSLTTAYLQWSSLKASDTGIYYCARLD
ARVDAGWQLDSWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCL
VKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGT
QTYICNVNHKPSNTKVDKRVEPK
Ligand information
>6dcw Chain T (length=9) Species:
9606
(Homo sapiens) [
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YKPVDLSKV
Receptor-Ligand Complex Structure
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PDB
6dcw
A common antigenic motif recognized by naturally occurring human VH5-51/VL4-1 anti-tau antibodies with distinct functionalities.
Resolution
2.0 Å
Binding residue
(original residue number in PDB)
W33 Y52 D54 D56 A97 R98 V99 W100C
Binding residue
(residue number reindexed from 1)
W33 Y52 D55 D57 A101 R102 V103 W107
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:6dcw
,
PDBe:6dcw
,
PDBj:6dcw
PDBsum
6dcw
PubMed
29855358
UniProt
P01857
|IGHG1_HUMAN Immunoglobulin heavy constant gamma 1 (Gene Name=IGHG1)
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