Structure of PDB 6cnl Chain H Binding Site BS01

Receptor Information
>6cnl Chain H (length=186) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AKATRHIFLIRASQYHRTLTPLGREQAELTGLRLASLGLKFNKIVHSSMT
RAIETTDIISRHLPGVCKVSTDLLREGAPIEPDPPVWKPEAVQYYEDGAR
IEAAFRNYIHRADARQEEDSYEIFICHANVIRYIVCRALQFPPEGWLRLS
LNNGSITHLVIRPNGRVALRTLGDTGFMPPDKITRS
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6cnl Functional role of PGAM5 multimeric assemblies and their polymerization into filaments.
Resolution2.6 Å
Binding residue
(original residue number in PDB)
I212 H213 R214 Q243 G268 V270
Binding residue
(residue number reindexed from 1)
I109 H110 R111 Q140 G165 V167
Enzymatic activity
Enzyme Commision number 3.1.3.16: protein-serine/threonine phosphatase.
External links
PDB RCSB:6cnl, PDBe:6cnl, PDBj:6cnl
PDBsum6cnl
PubMed30705304
UniProtQ96HS1|PGAM5_HUMAN Serine/threonine-protein phosphatase PGAM5, mitochondrial (Gene Name=PGAM5)

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