Structure of PDB 6b45 Chain H Binding Site BS01

Receptor Information
>6b45 Chain H (length=333) Species: 208963 (Pseudomonas aeruginosa UCBPP-PA14) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LSTASVLAFERKLDPSDALMSAGAWAQRDASQEWPAVTVREKSVRGTISN
RLKTKDRDPAKLDASIQSPNLQTVDVANLPSDADTLKVRFTLRVLGGAGT
PSACNDAAYRDKLLQTVATYVNDQGFAELARRYAHNLANARFLWRNRVGA
EAVEVRINHIRQGEVARAWRFDALAIGLRDFKADAELDALAELIASGLSG
SGHVLLEVVAFARIGDGQEVFPSQELILDKGDKKGQKSKTLYSVRDAAAI
HSQKIGNALRTIDTWYPDEDGLGPIAVEPYGSVTSQGKAYRQPKQKLDFY
TLLDNWVLRDEAPAVEQQHYVIANLIRGGVFGE
Ligand information
>6b45 Chain M (length=60) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
cuaagaaauucacggcgggcuugauguccgcgucuaccugguucacugcc
guguaggcag
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Receptor-Ligand Complex Structure
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PDB6b45 Cryo-EM Structures Reveal Mechanism and Inhibition of DNA Targeting by a CRISPR-Cas Surveillance Complex.
Resolution3.5 Å
Binding residue
(original residue number in PDB)
A13 F14 E15 R16 V49 R50 L76 Q77 W149 R150 Q229 E230 L231 Q258 K259 N262 R265 S290 R332 G333 G334 V335
Binding residue
(residue number reindexed from 1)
A8 F9 E10 R11 V44 R45 L71 Q72 W144 R145 Q224 E225 L226 Q253 K254 N257 R260 S285 R327 G328 G329 V330
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005515 protein binding
Biological Process
GO:0051607 defense response to virus

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Molecular Function

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Biological Process
External links
PDB RCSB:6b45, PDBe:6b45, PDBj:6b45
PDBsum6b45
PubMed28985564
UniProtQ02MM1|CSY3_PSEAB CRISPR-associated protein Csy3 (Gene Name=csy3)

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