Structure of PDB 5w5r Chain H Binding Site BS01

Receptor Information
>5w5r Chain H (length=409) Species: 358 (Agrobacterium tumefaciens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VQPLARDAMAYVLAGGRGSRLKELTDRRAKPAVYFGGKARIIDFALSNAL
NSGIRRIGVATQYKAHSLIRHLQRGWDFFRPERNESFDILAATQWYEGTA
DAVYQNIDIIEPYAPEYMVILAGDHIYKMDYEYMLQQHVDSGADVTIGCL
EVPRMEATGFGVMHVNEKDEIIDFIEKPADPPGIPGNEGFALASMGIYVF
HTKFLMEALRRDAADPTSSRDFGKDIIPYIVEHGKAVAHRFADSCVRSDF
EHEPYWRDVGTIDAYWQANIDLTDVVPDLDIYDKSWPIWTYAEITPPAKF
VHDDEDRRGSAVSSVVSGDCIISGAALNRSLLFTGVRANSYSRLENAVVL
PSVKIGRHAQLSNVVIDHGVVIPEGLIVGEDPELDAKRFRRTESGICLIT
QSMIDKLDL
Ligand information
Ligand IDPYR
InChIInChI=1S/C3H4O3/c1-2(4)3(5)6/h1H3,(H,5,6)
InChIKeyLCTONWCANYUPML-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.385CC(=O)C(O)=O
OpenEye OEToolkits 1.7.6CC(=O)C(=O)O
ACDLabs 12.01O=C(C(=O)O)C
FormulaC3 H4 O3
NamePYRUVIC ACID
ChEMBLCHEMBL1162144
DrugBankDB00119
ZINCZINC000001532517
PDB chain5w5r Chain H Residue 503 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB5w5r Structural analysis reveals a pyruvate-binding activator site in theAgrobacterium tumefaciensADP-glucose pyrophosphorylase.
Resolution1.754 Å
Binding residue
(original residue number in PDB)		K44 S329 G330
Binding residue
(residue number reindexed from 1)		K38 S317 G318
Annotation score1
Enzymatic activity
Enzyme Commision number 2.7.7.27: glucose-1-phosphate adenylyltransferase.
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0008878 glucose-1-phosphate adenylyltransferase activity
GO:0016779 nucleotidyltransferase activity
Biological Process
GO:0005978 glycogen biosynthetic process
GO:0009058 biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:5w5r, PDBe:5w5r, PDBj:5w5r
PDBsum5w5r
PubMed30401744
UniProtP39669|GLGC_RHIRD Glucose-1-phosphate adenylyltransferase (Gene Name=glgC)

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