Structure of PDB 5mq0 Chain H Binding Site BS01

Receptor Information
>5mq0 Chain H (length=401) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
IKFQRENWEMIRSHVSPIISNLTMDNLQESHRDLFQVNILIGRNIICKNV
VDFTLNKQNGRLIPALSALIALLNSDIPDIGETLAKELMLMFVQQFNRKD
YVSCGNILQCLSILFLYDVIHEIVILQILLLLLEKNSLRLVIAVMKICGW
KLALVSKKTHDMIWEKLRYILQTQELSSTLRESLETLFEIRQKDYKSCEN
FNELTMAFDTLRQKLVEFKKKIYLVLKSSLSGDEAAHKLLKLKIANNLKK
SVVDIIIKSSLQESTFSKFYSILSERMITFHRSWQTAYNETFEQNYTQDI
EDYETDQLRILGKFWGHLISYEFLPMDCLEESCPQGRIFIKFLFQELVNE
LGLDELQLRLNSSKLDGMFPLEGDAEHIRYSINFFTAIGLGLLTEDMRSR
L
Ligand information
Receptor-Ligand Complex Structure
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PDB5mq0 Structure of a spliceosome remodelled for exon ligation.
Resolution4.17 Å
Binding residue
(original residue number in PDB)
K316 K322 F353 H354
Binding residue
(residue number reindexed from 1)
K243 K249 F280 H281
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003674 molecular_function
GO:0003723 RNA binding
Biological Process
GO:0000398 mRNA splicing, via spliceosome
GO:0006397 mRNA processing
GO:0008380 RNA splicing
Cellular Component
GO:0005634 nucleus
GO:0005681 spliceosomal complex
GO:0005684 U2-type spliceosomal complex
GO:0005737 cytoplasm
GO:0071013 catalytic step 2 spliceosome

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:5mq0, PDBe:5mq0, PDBj:5mq0
PDBsum5mq0
PubMed28076345
UniProtP53333|CWC22_YEAST Pre-mRNA-splicing factor CWC22 (Gene Name=CWC22)

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