Structure of PDB 5cp3 Chain H Binding Site BS01

Receptor Information
>5cp3 Chain H (length=212) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DVQLRESGPDLVTPSQSLSLTCTVTGYSITSGYSWHWNRQFPGNKLEWMG
YIHYSGSTNYNPSLRGRISITRDTSKNQFFLQLNSVTTEDTATYYCARYG
GYWGQGTSVTVASAATTPPSVYPLAPGGGATNSMVTLGCLVKGYFPEPVT
VTWNSGSLSGGVHTFPAVLQSDLYTLSSSVTVPSSTWPSETVTCNVAHPA
SSTKVDKKIVPR
Ligand information
Ligand IDYTZ
InChIInChI=1S/C9H9N3O2S2/c10-7-1-3-8(4-2-7)16(13,14)12-9-11-5-6-15-9/h1-6H,10H2,(H,11,12)
InChIKeyJNMRHUJNCSQMMB-UHFFFAOYSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.7.6c1cc(ccc1N)S(=O)(=O)Nc2nccs2
ACDLabs 12.01O=S(=O)(Nc1nccs1)c2ccc(N)cc2
CACTVS 3.370Nc1ccc(cc1)[S](=O)(=O)Nc2sccn2
FormulaC9 H9 N3 O2 S2
Name4-amino-N-(1,3-thiazol-2-yl)benzenesulfonamide;
Sulfathiazole
ChEMBLCHEMBL437
DrugBankDB06147
ZINCZINC000000121458
PDB chain5cp3 Chain A Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5cp3 Class-specific Monoclonal Antibodies and Dihydropteroate Synthase in Bioassays used for the Detection of Sulfonamides: Structural Insights into Recognition Diversity.
Resolution1.99 Å
Binding residue
(original residue number in PDB)		H36 R98 Y99 G100 G101 W103
Binding residue
(residue number reindexed from 1)		H36 R98 Y99 G100 G101 W103
Annotation score1
External links