Structure of PDB 4ygd Chain H Binding Site BS01

Receptor Information
>4ygd Chain H (length=70) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MSPQELQLHYFKMHDYDGNNLLDGLELSTAITHAPLMSEDELINIIDGVL
RDDDKNNDGYIDYAEFAKSL
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain4ygd Chain H Residue 501 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB4ygd Crystallographic snapshots of the EF-hand protein MCFD2 complexed with the intracellular lectin ERGIC-53 involved in glycoprotein transport.
Resolution2.51 Å
Binding residue
(original residue number in PDB)		D81 D83 N85 L87 E92
Binding residue
(residue number reindexed from 1)		D15 D17 N19 L21 E26
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding

View graph for
Molecular Function
External links
PDB RCSB:4ygd, PDBe:4ygd, PDBj:4ygd
PDBsum4ygd
PubMed32356523
UniProtQ8NI22|MCFD2_HUMAN Multiple coagulation factor deficiency protein 2 (Gene Name=MCFD2)

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