Structure of PDB 4u67 Chain H Binding Site BS01

Receptor Information
>4u67 Chain H (length=134) Species: 243230 (Deinococcus radiodurans R1 = ATCC 13939 = DSM 20539) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MIMPQSRLDVADNSGAREIMCIRVLNSGIGGKGLTTGGGGNKRYAHVGDI
IVASVKDAAPRGAVKAGDVVKAVVVRTSHAIKRADGSTIRFDRNAAVIIN
NQGEPRGTRVFGPVARELRDRRFMKIVSLAPEVL
Ligand information
>4u67 Chain X (length=2667) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ggucaagauaguaaggguccacgguggaugcccuggcgcuggagccgaug
aaggacgcgauuaccugcgaaaagccccgacgagcuggagauacgcuuug
acucggggauguccgaauggggaaacccaccucguaagagguauccgcaa
ggaugggaacucagggaacugaaacaucucaguaccugaaggagaagaaa
gagaauucgauuccguuaguagcggcgagcgaacccggaucagcccaauc
aagccgaaguggcuggaaagcuacaccucagaaggugagaguccuguagg
cgaacgagaggucguuguucgugaaacgaugacugaauccgcgcggacca
ccgcgcaaggcuaaauacucccagugaccgauagcgcauaguaccgugag
ggaaaggugaaaagaaccccgggaggggagugaaagagaaccugaaaccg
uggacuuacaagcagucauggcaccuuaugcguguuauggcgugccuauu
gaagcaugagccggcgacuuagaccugacgugcgagcuuaaguugaaaaa
cggaggcggagcgaaagcgaguccgaauagggcggcauuaguacgucggg
cuagacucgaaaccaggugagcuaagcaugaccagguugaaacccccggg
gggcggaggaccgaaccggugccugcugaaacagucucggaugaguugug
uuuaggagugaaaagcuaaccgaaccuggagauagcuaguucuccccgaa
auguauugagguacagccucggauguugaccauguccuguagagcacuca
caaggcuaaaaccuuaugaaacuccgaaggggcacgcguuuaguccggga
gugaggcugcgagagcuaacuuccguagccgagagggaaacaacccagac
caucagcuaaggucccuaaaugaucgcucagugguuaaggaugugucguc
gcauagacagccaggagguuggcuuagaagcagccaccaagagugcguaa
uagcucacuggucgagugacgaugcgccgaaaaugaucggggcucaagug
aucuaccgaagcuauggauucaacucgccgaguugucugguaggggagcg
uucaguccgcggagaagccauaccggaaggagugguggagccgacugaag
ugcggaugccggcaugaguaacgauaaaagaagugagaaucuucuucgcc
guaaggacaaggguuccuggggaagggucguccgcccagggaaagucggg
accuaaggugaggccgaacggcgcagccgauggacagcaggucaagauuc
cugcaccgaucauguggagugauggagggacgcauuacgcuauccaaugc
caagcuauggcuaugcugguugguacgcucaagggcgaucgggucagaaa
aucuaccggucacaugccucagacguaucgggagcuuccucggaagcgaa
guuggaaacgcgacggugccaagaaaagcuucuaaacguugaaacaugau
ugcccguaccgcaaaccgacacagguguccgagugucaaugcacuaaggc
gcgcgagagaacccucguuaaggaacuuugcaaucucaccccguaacuuc
ggaagaagggguccccacgcuucgcguggggcgcagugaauaggcccagg
cgacuguuuaccaaaaucacagcacucugccaacacgaacaguggacgua
uagggugugacgccugcccggugccggaaggucaaguggagcggugcaag
cugcgaaaugaagccccggugaacggcuaagguagcgaaauuccuugucg
gguaaguuccgaccugcacgaaaggcguaacgaucugggcgcugucucaa
cgagggacucggugaaauugaauuggcuguaaagaugcggccuacccgua
gcaggacgaaaagaccccguggagcuuuacuauagucuggcauugggauu
cggguuucuagaaacuuggauuucuaaccugaaaaaucacuuucggggac
cgugcuuggcggguaguuugacuggggcggucgccucccaaaauguaacg
gaggcgcccaaaggucaccucaagacgguuggaaaucgucuguagagcgc
aaagguagaagguggcuugacugcgagacugacacgucgagcagggagga
aacucgggcuuagugaaccggugguaccguguggaagggccaucgaucaa
cggauaaaaguuaccccggggauaacaggcugaucucccccgagagucca
uaucggcggggagguuuggcaccucgaugucggcucgucgcauccugggg
cugaagaaggucccaaggguugggcuguucgcccauuaaagcggcacgcg
agcuggguucagaacgucgugagacaguucggucucuauccgcuacgggc
gcaggagaauugaggggaguugcuccuaguacgagaggaccggagugaac
ggaccgcuggucucccugcugucguaccaacggcacaugcaggguagcua
uguccggaacggauaaccgcugaaagcaucuaagcgggaagccagcccca
agaugaguucucccacugcagguaagacucccggaagaccaccggguuaa
gaggccaggcgugcacgcauagcaauguguucagcggacuggugcucauc
agucgaggucuugacca
<<<<<<<<......<<<<<<<<<<<....<<<..<<<<<<<<<<<<....
..<<<<<<.((..((.>>>.....<<<<<<...<<.))..))..>>....
..>>>>>>...>>>....<<<....>>><<<<<....>>>>><<<<....
>>>>>>...<<<<<<.....<......>......>>>>>.>.........
<<....>>...<<<<......<<.....>>.....>>>>...<<<.....
..<<<...<<<<<......>>>>>((......<<<.....))>>>...>>
>........<<<<<<<<.........>>>>>>>>......<<<<<..(((
(>>>>>..>>>......>>.>>>>>>.>>..............<<....>
>....>>.........<<<<....>>>>.............>....>>>>
>>>>>>>.......<<<<<<<<<<.......>>>>>>>>>>...<.<...
.....>.>.<<<<<<....<<<.<<<<<<<<<<..<<<...<<<....>>
>...>>>...<<....>>...<<......>>.........>>>>>>>>>>
>>>..<<.<...<<<<<<.....<<<<<<<<<..<<<.....<<<<<.>>
>>>......>>>...<<<..<.<<........>>.>.>>>....>>>>>>
>>>...<<<.....>>>......>>>>>>......>.>>..<<<<<<...
.<<<<<....>>>>><<<<<<<<<...<<<..<<<<<<...<<<...<<<
.<<<<......>>>>.>>>..>>.>...>>>>>>...>>>..>>>>>>>.
>>..<<<<<<<.<<......>>.>>>>>>>....<<<......>>>...<
<<<.<<<...<<<(((.....<<<<<<...........<<..<<<<<<<<
<........<<<<<......<<<<.......>>>>.........<<....
..>>...>>>>>....>>>>>>>>>.>>..........)))......>>>
>>>.>>>...>>>>>>><..<<<<<<...>>>>>>..>....>>>>>><.
<<<<<<<.<<......<<<<<.<<....>>.>>>>>...>>.>>>>>>>.
.>.....>>>>>><......<<.....<<<<<<.......>>>>>><<<<
....<<<<<.<<...<<<<<<...<<.....>>.>>>>>>....((<<<<
.<<...<<<...<<<<..>>>>...>>>...>>...<<<<<........>
>>>>))<<<<<<<<<...<<...<<<<....<<<<..<<<..<<<<<.<<
<<.<<...[[....>>>>>><<<<<<<.<<..<<<<<<<<<<...<<...
..>>.>>>>>>....>>>>..>>>>>>>>>...<<<<<....>>>>>...
.>>>>>...>>>...>>>>.........>>>>...>>......>>>>>>>
>>>>>>..>>.....<<......>>>>>>>.<<<<<....>>>>>..>>>
>..<<<<....<<<<<<<<.<<.........<.....<<<<<.....<..
>......>>>>><<<<<<<<...>>>>>>>>............<<<<<<<
<<..<<...........>>..<<<<<<<.....<<<.....>>>......
.>>>>>>>.<<<<<..<<..<<<<<<<..<<<...<<...<<<<<....>
>>>>...>>...>>>>>>>>..>>>>........<...........<<<<
<<.....>>>>>>.....>....>>>>>..>>.>>>>>>>..>..>>.>>
>>>>>>.>>>>>>.....>.....<<<<<........>>>>>..<<<<<<
<<.<<<.........<<<<.<<<<<<..<<<<<.<<<.<<<<<.<<<<<<
<<<<<<<<<>>>>>>>>>>>>>>>...<<<<<<.......>.>>>>>...
.>>>>>.>>>..>>>>>..<<<<.....>>>><<<<<<...........>
>>>>>..<<...<<<<<<<...<<<<<<.......>>>>>>.....<<..
.(((>>....>>>>>>>...<<<<..<<<......>>>..>>>>.<<<..
..>>>.>>))).......<<<<<<<.<<..))))..>>>>>>>>>.....
........>>>>..>>>>>>.......<<<<...<<<<<<...<<.....
..>>...>>>>>>....>>>.>.......<<<<<.<<<<<<..<<<<<<<
<<......>>>>>>>..>>.<<<<<.....>>>>>.....>>>>>..>..
.>>>.>>....<<<<<<<....>>>.>>>>........>>>>>>>>>>>.
...<<<<<<<...<<<<..<<<<<<<...............>>>>>>>.<
<<<<...<<<<...<<<<<<<<<<<.]].>>>>>>...>>>>>...>>>>
.>>>>>....<<....<<<<<...........>>>>>....>>..>>>>.
......>>>>>>>..<<..>>....<<<<<<<<<.......>>>>>....
<<<<<<<<.<<<....<<<<<....>>>>>...>>>..>>>>>.>>>...
>>>>....>>>>>>>>.
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4u67 The Ribosomal Protein uL22 Modulates the Shape of the Protein Exit Tunnel.
Resolution3.65 Å
Binding residue
(original residue number in PDB)
M1 M3 Q5 S6 I22 R23 N26 T35 G37 G38 G39 G40 N41 K42 R43 Y44 S54 K56 K82 N94
Binding residue
(residue number reindexed from 1)
M1 M3 Q5 S6 I22 R23 N26 T35 G37 G38 G39 G40 N41 K42 R43 Y44 S54 K56 K82 N94
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
GO:0070180 large ribosomal subunit rRNA binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0015934 large ribosomal subunit
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function

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Biological Process

View graph for
Cellular Component
External links
PDB RCSB:4u67, PDBe:4u67, PDBj:4u67
PDBsum4u67
PubMed28689968
UniProtQ9RXJ2|RL14_DEIRA Large ribosomal subunit protein uL14 (Gene Name=rplN)

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