Structure of PDB 4ris Chain H Binding Site BS01

Receptor Information
>4ris Chain H (length=228) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EVQLVQSGAEVKKPGESLKISCKGSGYSFTSYWIGWVRQMPGKGLEWMGI
IYPGDSDTRYSPSFQGQVTISADKSISTAYLQWSSLKASDTAMYYCARLG
GRYYYDSSGYYYFDYWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAA
LGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSS
SLGTQTYICNVNHKPSNTKVDKRVEPKS
Ligand information
>4ris Chain P (length=14) Species: 11676 (Human immunodeficiency virus 1) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
RDKKQKVHALFYKA
Receptor-Ligand Complex Structure
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PDB4ris Structural analysis of the unmutated ancestor of the HIV-1 envelope V2 region antibody CH58 isolated from an RV144 vaccine efficacy trial vaccinee.
Resolution2.3 Å
Binding residue
(original residue number in PDB)
W33 Y52 D54 D56 L95 Y99 Y100 Y100A D100B G100E Y100G
Binding residue
(residue number reindexed from 1)
W33 Y52 D55 D57 L99 Y103 Y104 Y105 D106 G109 Y111
External links