Structure of PDB 4or5 Chain H Binding Site BS01

Receptor Information
>4or5 Chain H (length=48) Species: 11706 (HIV-1 M:B_HXB2R) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MEPVDPRLEPWKHPGSQPKTACTNCYCKKCCFHCQVCFITKALGISYG
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain4or5 Chain H Residue 101 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB4or5 Crystal structure of HIV-1 Tat complexed with human P-TEFb and AFF4.
Resolution2.9 Å
Binding residue
(original residue number in PDB)		C22 H33 C34 C37
Binding residue
(residue number reindexed from 1)		C22 H33 C34 C37
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0001070 RNA-binding transcription regulator activity
Biological Process
GO:0050434 positive regulation of viral transcription
Cellular Component
GO:0042025 host cell nucleus

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4or5, PDBe:4or5, PDBj:4or5
PDBsum4or5
PubMed24727379
UniProtP04608|TAT_HV1H2 Protein Tat (Gene Name=tat)

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