Structure of PDB 4inh Chain H Binding Site BS01

Receptor Information
>4inh Chain H (length=168) Species: 524364 (Norovirus Hu/1968/US) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DKAPPTLWSRVTKFGSGWGFWVSPTVFITTTHVVPTGVKEFFGEPLSSIA
IHQAGEFTQFRFSKKMRPDLTGMVLEEGCPEGTVCSVLIKRDSGELLPLA
VRMGAIASMRIQGRLVHGQSGMLLMDLGTIPGDCGAPYVHKRGNDWVVCG
VHAAATKSGNTVVCAVQA
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4inh Structural basis of substrate specificity and protease inhibition in norwalk virus.
Resolution1.7 Å
Binding residue
(original residue number in PDB)		H30 I109 Q110 T134 P136 C139 A158 A159 A160
Binding residue
(residue number reindexed from 1)		H32 I111 Q112 T129 P131 C134 A153 A154 A155
Enzymatic activity
Enzyme Commision number 2.7.7.48: RNA-directed RNA polymerase.
3.4.22.66: calicivirin.
3.6.1.15: nucleoside-triphosphate phosphatase.
Gene Ontology
Molecular Function
GO:0004197 cysteine-type endopeptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:4inh, PDBe:4inh, PDBj:4inh
PDBsum4inh
PubMed23365454
UniProtQ83883|POLG_NVN68 Genome polyprotein (Gene Name=ORF1)

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