Structure of PDB 3mnn Chain H Binding Site BS01

Receptor Information
>3mnn Chain H (length=95) Species: 8355 (Xenopus laevis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KTRKESYAIYVYKVLKQVHPDTGISSKAMSIMNSFVNDVFERIAGEASRL
AHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSAK
Ligand information
>3mnn Chain I (length=145) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
atcaatatccacctgcagatactaccaaaagtgtatttggaaactgctcc
atcaaaaggcatgttcagctgaatcagctgaacatgccttttgatggagc
agtttccaaatacacttttggtagtatctgcaggtggatattgat
Receptor-Ligand Complex Structure
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PDB3mnn A ruthenium antimetastasis agent forms specific histone protein adducts in the nucleosome core
Resolution2.5 Å
Binding residue
(original residue number in PDB)		R30 K31 E32 S33 Y37
Binding residue
(residue number reindexed from 1)		R3 K4 E5 S6 Y10
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Cellular Component
GO:0000786 nucleosome
GO:0005634 nucleus
GO:0005694 chromosome

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Molecular Function
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Cellular Component
External links
PDB RCSB:3mnn, PDBe:3mnn, PDBj:3mnn
PDBsum3mnn
PubMed21344528
UniProtP02281|H2B11_XENLA Histone H2B 1.1

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