Structure of PDB 3lpe Chain H Binding Site BS01

Receptor Information
>3lpe Chain H (length=59) Species: 2190 (Methanocaldococcus jannaschii) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MRACLKCKYLTNDEICPICHSPTSENWIGLLIVINPEKSEIAKKAGIDIK
GKYALSVKE
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain3lpe Chain H Residue 60 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB3lpe Spt4/5 stimulates transcription elongation through the RNA polymerase clamp coiled-coil motif.
Resolution1.9 Å
Binding residue
(original residue number in PDB)		C4 C7 C16 C19
Binding residue
(residue number reindexed from 1)		C4 C7 C16 C19
Annotation score1
Enzymatic activity
Enzyme Commision number 2.7.7.6: DNA-directed RNA polymerase.
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0046872 metal ion binding
Biological Process
GO:0006355 regulation of DNA-templated transcription

View graph for
Molecular Function
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Biological Process
External links
PDB RCSB:3lpe, PDBe:3lpe, PDBj:3lpe
PDBsum3lpe
PubMed20197319
UniProtQ57839|SPT4_METJA Transcription elongation factor Spt4 (Gene Name=spt4)

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