Structure of PDB 3hym Chain H Binding Site BS01

Receptor Information
>3hym Chain H (length=302) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QENLDVVVSLAERHYYNCDFKMCYKLTSVVMEKDPFHASCLPVHIGTLVE
LNKANELFYLSHKLVDLYPSNPVSWFAVGCYYLMVGHKNEHARRYLSKAT
TLEKTYGPAWIAYGHSFAVESEHDQAMAAYFTAAQLMKGCHLPMLYIGLE
YGLTNNSKLAERFFSQALSIAPEDPFVMHEVGVVAFQNGEWKTAEKWFLD
ALEKIKAIGNEVTVDKWEPLLNNLGHVCRKLKKYAEALDYHRQALVLIPQ
NASTYSAIGYIHSLMGNFENAVDYFHTALGLRRDDTFSVTMLGHCIEMYI
GD
Ligand information
>3hym Chain G (length=25) Species: 9606 (Homo sapiens) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
MLRRKPTRLELKLDDIEEFENIRKD
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3hym Insights into anaphase promoting complex TPR subdomain assembly from a CDC26-APC6 structure.
Resolution2.8 Å
Binding residue
(original residue number in PDB)		Y242 Y243 C245 H342 A345 M364 L369 Y373 L376 D401 F403 H406 E407 V410 E445 P446 N449 N450 R456 K457 N478 S480 Y487 S490 L491 F514 M518 M525
Binding residue
(residue number reindexed from 1)		Y15 Y16 C18 H115 A118 M137 L142 Y146 L149 D174 F176 H179 E180 V183 E218 P219 N222 N223 R229 K230 N251 S253 Y260 S263 L264 F287 M291 M298
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:3hym, PDBe:3hym, PDBj:3hym
PDBsum3hym
PubMed19668213
UniProtQ13042|CDC16_HUMAN Cell division cycle protein 16 homolog (Gene Name=CDC16)

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