Structure of PDB 2uwe Chain H Binding Site BS01
Receptor Information
>2uwe Chain H (length=275) Species:
9606
(Homo sapiens) [
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GSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAP
WIEQEGPEYWDGETRKVKAHSQTHRVDLGTLRGYYNQSEAGSHTVQRMYG
CDVGSDWRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQTTKHKWEAA
HVAEQLRAYLEGACVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEAT
LRCWALSFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVP
SGQEQRYTCHVQHEGLPKPLTLRWE
Ligand information
>2uwe Chain J (length=9) Species:
9606
(Homo sapiens) [
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ALWGFFPVL
Receptor-Ligand Complex Structure
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PDB
2uwe
Single Mhc Mutation Eliminates Enthalpy Associated with T Cell Receptor Binding.
Resolution
2.4 Å
Binding residue
(original residue number in PDB)
Y7 F9 E63 K66 V67 A69 H70 T73 D77 Y84 Y99 Y116 T143 W147 Q155 L156 Y159 W167 Y171
Binding residue
(residue number reindexed from 1)
Y7 F9 E63 K66 V67 A69 H70 T73 D77 Y84 Y99 Y116 T143 W147 Q155 L156 Y159 W167 Y171
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:2uwe
,
PDBe:2uwe
,
PDBj:2uwe
PDBsum
2uwe
PubMed
17825839
UniProt
P04439
|HLAA_HUMAN HLA class I histocompatibility antigen, A alpha chain (Gene Name=HLA-A)
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