Structure of PDB 2r8s Chain H Binding Site BS01
Receptor Information
>2r8s Chain H (length=218) Species:
10090
(Mus musculus) [
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EVQLVESGGGLVQPGGSLRLSCAASGFNLYSSSIHWVRQAPGKGLEWVAY
ISSSYGYTYYADSVKGRFTISADTSKNTAYLQMNSLRAEDTAVYYCARRA
AGMSTYGFDYWGQGTLVTVSSASTKGPSVFPLAPSGTAALGCLVKDYFPE
PVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNV
NHKPSNTKVDKKVEPKSC
Ligand information
>2r8s Chain R (length=159) [
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ggaauugcgggaaaggggucaacagccguucaguaccaagucucagggga
aacuuugagauggccuugcaaaggguaugguaauaagcugacggacaugg
uccuaacacgcagccaaguccuaagucaacagaucuucuguugauaugga
ugcaguuca
.....<<<<.<...<<<<<<.....<<<.<<<<.<<...<<<<<<<<<..
..>>>>>>>>>..<<.......>>.....>>......>>>>>>>....>>
>>>>..>.>>>><<...<<<<...<<<<<<<<.....>>>>>>>>..>>>
>...>>...
Receptor-Ligand Complex Structure
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PDB
2r8s
Synthetic antibodies for specific recognition and crystallization of structured RNA
Resolution
1.95 Å
Binding residue
(original residue number in PDB)
G26 F27 N28 Y30 S52 S54 Y57 R98 R99 A100 G102 M103 S104 T105 Y106 G107 D109
Binding residue
(residue number reindexed from 1)
G26 F27 N28 Y30 S52 S54 Y57 R98 R99 A100 G102 M103 S104 T105 Y106 G107 D109
Binding affinity
PDBbind-CN
: Kd=51nM
External links
PDB
RCSB:2r8s
,
PDBe:2r8s
,
PDBj:2r8s
PDBsum
2r8s
PubMed
18162543
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